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Cidofovir
go.drugbank.com/drugs/DB00369ApprovedInvestigationalCidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] I...
Categories: Heterocyclic Compounds, 1-Ring, Antivirals for Systemic UseSynonyms: (S)-(3-(4-amino-2-Oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid, ({[(S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acidCoagulation factor VIIa Recombinant Human
go.drugbank.com/drugs/DB00036ApprovedInvestigationalRecombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. … NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Products: NOVOSEVEN RT 1 MG, NOVOSEVEN RT 1 MG (50 KIU) ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜTetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate
go.drugbank.com/drugs/DB14106ApprovedInvestigationalTetrakis (2-methoxyisobutylisocyanide) copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for assessing myocardial perfusion.[L12744]
Products: STAMICIS 1 mg Kit for Radiopharmaceutical Preparation, MIBITEC 1 mg Kit für ein radioaktives ArzneimittelTenofovir alafenamide
go.drugbank.com/drugs/DB09299ApprovedInvestigational[A178327] Tenofovir alafenamide is indicated to treat chronic hepatitis B,[L6241] treat HIV-1,[L4388,L6277,L6280,L6283] and prevent HIV-1 infections. … Tenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when compared to the counterpart [tenofovir disoproxil].
Mixtures: GENVOYA FILM COATED TABLET 150 MG/150 MG/200 MG/10 MG, DESCOVY (200/10 MG)Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseDiazoxide
go.drugbank.com/drugs/DB01119ApprovedInvestigationalFDA-approved therapy for this condition. … Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.
Products: AZOXID® 50 MG/ML SUSPENSION ORAL, UPGLYCEM® 50 MG/ML. SUSPENSIÓN ORALTravoprost
go.drugbank.com/drugs/DB00287ApprovedInvestigationalrisk for developing off-target side effects. … Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective FP prostanoid receptor agonist.
Mixtures: DuoTrav Eye Drops, Solution (5mg/40mcg) per mL, TRAVAPRESS DUO 40 MCG+5 MG/ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADETSynonyms: isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[(α,α,α-trifluoro-m-tolyl)oxy]-1-butenyl}cyclopentyl)-5-heptenoate, ISOPROPYL (Z)-7-((1R,2R,3R,5S)-3,5-DIHYDROXY-2-((1E,3R)-3-HYDROXY-4-((.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-M-TOLYL)OXY)-1-BUTENYL)CYCLOPENTYL)-5-HEPTENOATERoflumilast
go.drugbank.com/drugs/DB01656ApprovedInvestigational[L46541] On December 15, 2023, the FDA approved a new topical foam formulation of roflumilast for the treatment of seborrheic dermatitis in patients aged 9 years and older.[L49281] … [A251385] PDE4 is a major cyclic-3',5′-adenosinemonophosphate (cyclic AMP, cAMP)-metabolizing enzyme [L37564] expressed on nearly all immune and pro-inflammatory cells, in addition to structural cells
Categories: Heterocyclic Compounds, 1-Ring, Antipsoriatics for Topical UseProducts: ROFLUNG 0,5 MG SAŞE ,30 SAŞE, ROFLUNG 0,5 MG SAŞE ,90 SAŞELanadelumab
go.drugbank.com/drugs/DB14597ApprovedInvestigationalLanadelumab, also known as DX-2930, is a human IgG1 monoclonal antibody designed for subcutaneous self-injection. … [L4538] It is a fully human immunoglobulin, k-light-chain made in recombinant Chinese Hamster Ovary cells.
Products: TAKHZYRO 300 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET, TAKHZYRO 300 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADETPropylene glycol
go.drugbank.com/drugs/DB01839ApprovedInvestigationalA clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Mixtures: LUBTANE %0,4 + %0,3 LUBRİKANT GÖZ DAMLASI, ÇÖZELTİ, 1 ADET, 10 ML, DIYENIL 100 ML LOSYONCategories: Compounds used in a research, industrial, or household settingEntrectinib
go.drugbank.com/drugs/DB11986ApprovedInvestigational[L8081] It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors. … [L8207] Entrectinib's approved use is meant as a last line of therapy due to its accelerated approval based on early trial data.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamide