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Treprostinil
go.drugbank.com/drugs/DB00374ApprovedInvestigational[A248770,A248775] The use of more stable alternatives such as treprostinil provides patients with PAH with more treatment options.
Dexchlorpheniramine maleate
go.drugbank.com/drugs/DB09555ApprovedDexchlorpheniramine is the S-enantiomer of chlorpheniramine which is a 1st generation anti-histamine. Dexchlorpheniramine has more pharmacological activity than the R and so is more potent than the racemic mixture.
Ledipasvir
go.drugbank.com/drugs/DB09027ApprovedTreatment options for chronic Hepatitis C have advanced significantly since 2011, with the development of Direct Acting Antivirals (DAAs) such as ledipasvir. … Since 2014, ledipasvir has been available as a fixed dose combination product with [sofosbuvir] (tradename Harvoni) used for the treatment of chronic Hepatitis C.
Dichloralphenazone
go.drugbank.com/drugs/DB01495ApprovedIllicitIt is a US Schedule IV drug and its clinical use is limited.
Diosmetin
go.drugbank.com/drugs/DB11259ApprovedIt also acts as a weak TrkB receptor agonist [A27230].
Levomenol
go.drugbank.com/drugs/DB13153ApprovedBisabolol, or more formally α-(−)-bisabolol or also known as levomenol, (-)-alpha-Bisabolol is found in fats and oils. (-)-alpha-Bisabolol is isolated from essential oil of Matricaria chamomilla (German
Idebenone
go.drugbank.com/drugs/DB09081ApprovedInvestigationalIdebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC).
Ceritinib
go.drugbank.com/drugs/DB09063ApprovedInvestigationalThis occurrence led to development of novel second-generation ALK inhibitors such as ceritinib to overcome crizotinib resistance.
Magnesium chloride
go.drugbank.com/drugs/DB09407ApprovedInvestigationalMagnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Bevantolol
go.drugbank.com/drugs/DB01295InvestigationalBevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension.