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Displaying results 2121 - 2130 of 10000 in total
  1. Target

    GTP-binding protein Rheb

    go.drugbank.com/bio_entities/BE0004594
    TargetHumans

    In response to nutrients, growth factors or amino acids, specifically activates the protein kinase activity of MTOR, the catalytic component of the mTORC1 complex: acts by causing a conformational change … In response to starvation, RHEB is inactivated by the TSC-TBC complex, preventing activation of mTORC1 (PubMed:24529379, PubMed:33157014). Has low intrinsic GTPase activity (PubMed:15340059)

    Synonyms: Ras homolog enriched in brain
  2. Target

    Protein RecA

    go.drugbank.com/bio_entities/BE0001257
    TargetDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

    Probably involved in base excision repair (PubMed:19303848). … Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded

    Synonyms: Recombinase A
  3. Target

    Protein RecA

    go.drugbank.com/bio_entities/BE0003084
    TargetShigella flexneri

    Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded

    Synonyms: Recombinase A
  4. Indication

    Degenerative Joint Disease of Hip

    go.drugbank.com/conditions/DBCOND0110588
    Drugs: Diacerein
    Synonyms: O/A, Osteoarthritis in the Hip Joint
  5. Target

    Monoamine oxidase

    go.drugbank.com/bio_entities/BE0004909
    TargetEnzymeHumans

    of neuroactive and vasoactive amines in the central nervous system and peripheral tissues (PubMed:18391214, PubMed:20493079, PubMed:24169519, PubMed:8316221). … Catalyzes the oxidative deamination of primary and some secondary amine such as neurotransmitters, with concomitant reduction of oxygen to hydrogen peroxide and has important functions in the metabolism

    Polypeptides: Amine oxidase [flavin-containing] ASynonyms: MAO-A, Monoamine oxidase type A
  6. Drug

    Atracurium besylate

    go.drugbank.com/drugs/DB00732
    Approved

    A non-depolarizing neuromuscular blocking agent with short duration of action. … Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents

    Categories: Heterocyclic Compounds, 2-RingProducts: ATRACURIUM LABATEC IV SOLUTION FOR INJECTION 10MG/ML, ./5 มล. ชนิดฉีด)
  7. Drug

    Naftifine

    go.drugbank.com/drugs/DB00735
    Approved

    Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum

    International brands: A MeiProducts: EXODERIL %1 KREM, 15 G, EXODERIL %1 KREM, 30 G
  8. Drug

    Serine

    go.drugbank.com/drugs/DB00133
    ApprovedInvestigationalNutraceutical

    A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids.

    Mixtures: NUTRIPLUS LIPID SENZA ELETTROLITI, NUTRIPLUS LIPID SENZA ELETTROLITISynonyms: (S)-2-Amino-3-hydroxypropanoic acid, L-Serine
  9. Indication

    Glabellar Frown Lines (GL)

    go.drugbank.com/conditions/DBCOND0081153
    Drugs: Botulinum toxin type A
    Synonyms: Glabellar Lines, Glabellar Frown Lines
  10. Drug

    Clonazepam

    go.drugbank.com/drugs/DB01068
    ApprovedIllicitInvestigational

    [FDA Label][A175438,A175441,L5572,F3763,F3787,F3796] Since being first patented in 1960 and then released for sale from Roche in the US in 1975,[T469,T472] clonazepam has experienced a storied history … in the treatment of the aforementioned medical conditions.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 InhibitorsSynonyms: 5-(2-chloro-phenyl)-7-nitro-1,3-dihydro-benzo[e][1,4]diazepin-2-one, 5-(2-chlorophenyl)-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-one