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Displaying results 2131 - 2140 of 10000 in total
  1. Drug

    5-(4-((2S,5S)-5-(4-chlorobenzyl)-2-methylmorpholino)piperidin-1-yl)-1H-1,2,4-triazol-3-amine

    go.drugbank.com/drugs/DB18065
    Investigational

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1H-1,2,4-Triazol-3-amine, 5-[4-[(2S,5S)-5-[(4-chlorophenyl)methyl]-2-methyl-4-morpholinyl]-1-piperidinyl]-, 5-[4-[(2S,5S)-5-[(4-Chlorophenyl)methyl]-2-methyl-4-morpholinyl]-1-piperidinyl]-1H-1,2,4-triazol-3-amine
  2. Drug

    Giroctocogene fitelparvovec

    go.drugbank.com/drugs/DB16174
    Investigational

    Giroctocogene fitelparvovec is under investigation in clinical trial NCT04370054 (Study to Evaluate the Efficacy and Safety of PF-07055480 in Moderately Severe to Severe Hemophilia a Adults).

    Synonyms: Aav2/6-b-domain-deleted blood coagulation factor viii, Dna (recombinant adeno-associated virus 6 vector pf-07055480 human b-domain-deleted blood-coagulation factor viii-specifying)
  3. Drug

    Zopapogene imadenovec

    go.drugbank.com/drugs/DB24672
    ApprovedInvestigational

    [L54081] Zopapogene imadenovec is a non-replicating adenoviral vector–based immunotherapy that expresses a fusion antigen from selected regions of HPV-6/11 proteins to elicit an immune response in RRP. … Recurrent respiratory papillomatosis (RRP) is a rare, debilitating disease driven by chronic human papillomavirus (HPV) 6 or 11 infection and characterized by recurrent benign tumors in the respiratory

    Synonyms: DNA (recombinant replication-deficient Gorilla gorilla gorilla adenovirus strain GC4 vector PRGN-2012 human cytomegalovirus promoter plus human papillomavirus 6/11 E2, E4, E6, E7 protein 11 epitope-containing, under control of a human cytomegalovirus (CMV) promoter and terminated with a 3' untranslated region and a simian virus 40 (SV40) polyadenylation signal
  4. Drug

    TT-232

    go.drugbank.com/drugs/DB12088
    Investigational

    Tln 232 is under investigation in clinical trial NCT00422786 (Phase II Study of CAP-232 in Patients With Refractory Metastatic Renal Cell Carcinoma).

    Salts: D-Phe-Cys-Tyr-D-Trp-Lys-Cys-Thr-NH2 (disulfide bridge: 2-6) acetateSynonyms: D-Phe-Cys-Tyr-D-Trp-Lys-Cys-Thr-NH2 (disulfide bridge: 2-6)
  5. Drug

    Dronedarone

    go.drugbank.com/drugs/DB04855
    ApprovedInvestigational

    [T28] Commonly marketed as Multaq®, dronedarone was approved by the FDA in July 2009 and Health Canada in August 2009. … [A34604] Similar to [amiodarone], dronedarone is a multichannel blocker that works to control rhythm and rate in atrial fibrillation.

    Categories: Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: N-(2-butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)-methanesulfonamide, N-(2-butyl-3-(p-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)methanesulfonamide
  6. Drug

    Guaiacol

    go.drugbank.com/drugs/DB11359
    Approved

    Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. … Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma.

    Mixtures: NOKTOS ® ADULTOS JARABE., Creo-rectal NourrissonSynonyms: 2-methoxyl-4-vinylphenol, 1-hydroxy-2-methoxybenzene
  7. Drug

    L-thioproline

    go.drugbank.com/drugs/DB02846
    Experimental

    Synonyms: 4-thiaproline, (R)-4-Thiazolidinecarboxylic acid
  8. Drug

    (2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE

    go.drugbank.com/drugs/DB07135
    Experimental

    Synonyms: (2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE
  9. Drug

    DSM-265

    go.drugbank.com/drugs/DB12397
    Investigational

    DSM265 has been used in trials studying the prevention and treatment of Malaria.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: Sulfur, (4-((2-(1,1-difluoroethyl)-5-methyl(1,2,4)triazolo(1,5-a)pyrimidin-7-yl)amino)phenyl)pentafluoro-, (oc-6-21)-, 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
  10. Drug

    6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL

    go.drugbank.com/drugs/DB08605
    Experimental

    Synonyms: 6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL