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Alfuzosin
go.drugbank.com/drugs/DB00346Approved[A228483] Alfuzosin is an alpha-1 adrenergic blocker used in the symptomatic treatment of BPH that works by relaxing the muscles in the prostate and bladder neck. … Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesSynonyms: (±)-N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furamide, N-[3-[(4-amino-6,7-dimethoxy-quinazolin-2-yl)- methyl-amino]propyl] tetrahydrofuran- 2-carboxamideEnprofylline
go.drugbank.com/drugs/DB00824ApprovedWithdrawnLong-term enprofylline administration may be associated with elevation in liver enzyme levels and unpredictable blood levels. … Enprofylline is a derivative of theophylline which shares bronchodilator properties.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 3-n-propylxanthine, 3-propylxanthineDusigitumab
go.drugbank.com/drugs/DB12363InvestigationalDusigitumab has been used in trials studying the treatment of Cancer, Advanced Solid Malignancies, Unresectable or Metastatic Hepatocellular Carcinoma (HCC), and Hormone-sensitive, HER-2 Negative Metastatic
Carisoprodol
go.drugbank.com/drugs/DB00395ApprovedThis drug is available by itself in an oral tablet or combined with aspirin, or in a fixed-dose combination with both aspirin and codeine [FDA label, F4060, F4069]. … for abuse in addition to a low risk of dependence [L5074].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesSynonyms: N-isopropy-2-methyl-2-propyl-1,3-propanediol dicarbamate, (1-methylethyl)carbamic acid 2-(((aminocarbonyl)oxy)methyl)-2-methylpentyl esterUnstable Angina Pectoris
go.drugbank.com/conditions/DBCOND0032056Synonyms: Angina at rest, (Angina: [crescendo] or [unstable] or [at rest]) or (preinfarction syndrome) or (impending infarction)T-5224
go.drugbank.com/drugs/DB05998ExperimentalT-5224 is an investigational drug developed to treat Sepsis-induced Acute Kidney Injury. It's mechanism of action is to inhibit c-Fos/activator protein-1.
Categories: Heterocyclic Compounds, 1-RingPotassium perchlorate
go.drugbank.com/drugs/DB09418ApprovedWithdrawnPotassium perchlorate is an inorganic salt with the chemical formula KClO4. It is a strong oxidizer with the lowest solubility of the alkali metal perchlorates. … Potassium perchlorate acts as a competitive inhibitor of iodine uptake by the thyroid gland and attenuates the production of the thyroid hormone.
Dermatophagoides farinae
go.drugbank.com/drugs/DB10400ApprovedInvestigationalThis combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Mixtures: SLITone ULTRA D. pteronyssinus/ D. farinae, Standardized Mite Mix, Dermatophagoides pteronyssinus and Dermatophagoides farinae, 10000 AU per mLProducts: Standardized Mite D Farinae, Standardized Mite D. farinaeTrifluoperazine
go.drugbank.com/drugs/DB00831ApprovedA phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Mixtures: Stelabid No 2, Stelabid No 1Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesDexchlorpheniramine maleate
go.drugbank.com/drugs/DB09555ApprovedDexchlorpheniramine is the S-enantiomer of chlorpheniramine which is a 1st generation anti-histamine. … Dexchlorpheniramine has more pharmacological activity than the R and so is more potent than the racemic mixture.
Mixtures: INTUNAL-F, Dexphen w/ CodeineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Inhibitors