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Dihydroorotate dehydrogenase A (fumarate)
go.drugbank.com/bio_entities/BE0002008TargetLactococcus lactis subsp. cremorisCatalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
Polypeptides: Dihydroorotate dehydrogenase A (fumarate)Synonyms: DHOD ABCL11 transcription factor A
go.drugbank.com/bio_entities/BE0019545TargetHumansMay function as a modulator of the transcriptional repression activity of NR2F2 (By similarity) … May play a role in hematopoiesis (By similarity). Essential factor in lymphopoiesis required for B-cell formation in fetal liver (By similarity).
Polypeptides: BCL11 transcription factor AEprosartan
go.drugbank.com/drugs/DB00876ApprovedInvestigationalEprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. … By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Mixtures: Teveten Plus 600 mg/12,5 mg Filmtabletten, TEVETEN PLUS 600 MG/12.5 MG FİLM KAPLI TABLET, 28 ADETCategories: Angiotensin 2 Receptor Blocker, Heterocyclic Compounds, 1-RingPerampanel
go.drugbank.com/drugs/DB08883ApprovedInvestigationalPerampanel is a noncompetitive AMPA glutamate receptor antagonist. … It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: 3-(2-Cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-oneQuinine
go.drugbank.com/drugs/DB00468ApprovedInvestigationalIt was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. … Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.
Mixtures: IRUDERM 1Categories: P-glycoprotein inhibitors, P-glycoprotein substratesPimecrolimus
go.drugbank.com/drugs/DB00337ApprovedInvestigationalIt is currently available as a topic cream used in the treatment of atopic dermatitis (eczema). … Pimecrolimus is an immunomodulating agent that was first marketed by Novartis under the trade name Elidel. It is now promoted in Canada by Galderma since early 2007.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Elidel 10 mg/g Creme, ELIDEL %1 KREM, 15 GCholecystokinin receptor type A
go.drugbank.com/bio_entities/BE0000402TargetHumansHas a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. … This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system
Polypeptides: Cholecystokinin receptor type ASynonyms: CCK-A receptorCholine-phosphate cytidylyltransferase A
go.drugbank.com/bio_entities/BE0000615EnzymeTargetHumansCatalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis
Polypeptides: Choline-phosphate cytidylyltransferase ASynonyms: CT A, CCT ACatabolite control protein A
go.drugbank.com/bio_entities/BE0001530TargetBacillus megateriumGlobal transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.
Polypeptides: Catabolite control protein A