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Trimetrexate
go.drugbank.com/drugs/DB01157ApprovedIt is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against pneumocystis pneumonia in AIDS patients. Myelosuppression is its dose-limiting toxic effect.
Mifepristone
go.drugbank.com/drugs/DB00834ApprovedInvestigationalCurrently under investigation for use in psychotic depression (phase 3 trials).
Categories: Hormonal Contraceptives for Systemic Use2,2'-Dibenzothiazyl disulfide
go.drugbank.com/drugs/DB14201Approved2,2'-Dibenzothiazyl disulfide is an accelerator used in the processing process for natural and synthetic rubber and plastic regeneration. It is also a known allergen and dermatological sensitizer.
Ataluren
go.drugbank.com/drugs/DB05016ApprovedWithdrawnThis drug does not yet have approval by the US Food and Drug Administration or by Health Canada for any indications. … Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk.
Meclocycline
go.drugbank.com/drugs/DB13092InvestigationalMeclocycline is under investigation in clinical trial NCT00385515 (Efficacy of SNX-1012 in the Treatment of Oral Mucositis) .
Categories: Anti-Acne Preparations for Topical Use, Antiinfectives for Treatment of AcneCentanafadine
go.drugbank.com/drugs/DB14841ApprovedInvestigational[L63934] The FDA approved centanafadine on July 24, 2026, for the treatment of ADHD in adults and pediatric patients 6 years of age and older weighing at least 20 kg; use is not recommended below that
Categories: Psychostimulants, Agents Used for ADHD and NootropicsTemoporfin
go.drugbank.com/drugs/DB11630ApprovedIt was first authorized for market by the European Medicines Agency in October 2001. It is currently available under the brand name Foscan.
Bosentan
go.drugbank.com/drugs/DB00559ApprovedInvestigationalBosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise pr...
Categories: Antihypertensives for Pulmonary Arterial HypertensionThrombomodulin Alfa
go.drugbank.com/drugs/DB05777ApprovedIt is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular
Autologous cultured chondrocytes
go.drugbank.com/drugs/DB10997ApprovedInvestigationalIt serves as an alternative repair treatment for patients with inadequate response to pre-existing surgical methods. … The surgical implantation shows a tolerable safety profile and efficacy up to 4 years, but it is not indicated for patients with osteoarthritis.