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Displaying results 2161 - 2170 of 10000 in total
  1. Drug

    TAS-106

    go.drugbank.com/drugs/DB06656
    Investigational

    TAS-106 is a new nucleoside antimetabolite. TAS-106 has demonstrated strong antitumor activity without serious toxicity in nude rat models bearing human tumours [A31693].

    Categories: Heterocyclic Compounds, 1-Ring, Nucleic Acids, Nucleotides, and NucleosidesSynonyms: 4-Amino-1-((2R,3R,4R,5R)-4-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidin-2-one, 3'-C-Ethynylcytidine
  2. Drug

    Sugammadex

    go.drugbank.com/drugs/DB06206
    ApprovedInvestigational

    Sugammadex (brand name Bridion) is marketed by Merck Sharp and Dohme, and was approved by the United States FDA on December 15, 2015. … Sugammadex provides a new treatment option to reverse the effects of those medications and possibly help patients recover sooner post-surgery.

    Categories: Compounds used in a research, industrial, or household settingProducts: BRIDION 500 MG/5 ML IV ENJEKSIYONLUK COZELTI ICEREN 10 FLAKON, SUGRİNO 500 MG/5 ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 10 ADET
  3. Drug

    LPT-99

    go.drugbank.com/drugs/DB17142
    Experimental

    Synonyms: 2-(4-(2,4-dichlorophenethyl)-3,6-dioxo-1-(2-(thiophen-2-yl)ethyl)piperazin-2-yl)-n-(2-(5-methoxy-1h-indol-3-yl)ethyl) acetamide, 2-(4-(2,4-dichlorophenethyl)-3,6-dioxo-1-(2-(thiophen-2-yl)ethyl)piperazin-2-yl)-n-(2-(5-methoxy-1h-indol-3-yl)ethyl)acetamide
  4. Drug

    Lisinopril

    go.drugbank.com/drugs/DB00722
    ApprovedInvestigational

    [L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. … [A184781,A184808,A184817] ACEIs are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.

    Mixtures: LISAM 10 mg/5 mg Tabletten, AMLIPIN 5 / 10 MG FILM TABLET, 30 ADETCategories: Compounds used in a research, industrial, or household setting, ACE Inhibitors and Diuretics
  5. Drug

    (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime

    go.drugbank.com/drugs/DB08553
    Experimental

    (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1h-pyrazol-4-yl)-2,3-dihydro-1h-inden-1-one oxime is a solid. This compound belongs to the phenylpyrazoles. … These are compounds containing a phenylpyrazole skeleton, which consists of a pyrazole bound to a phenyl group. It targets the protein serine/threonine-protein kinase B-raf.

    Synonyms: (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime
  6. Drug

    Ranitidine

    go.drugbank.com/drugs/DB00863
    ApprovedWithdrawn

    [L10818,F4253] The prevalence of GERD is thought to be 10-20% in western countries. … Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as [cimetidine] and [famotidine].

    Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingProducts: RANOBEL 50 MG/2 ML ENJEKTABL AMPUL, 5 ADET, ULCURAN 50 MG 10 AMPUL
  7. Drug

    Doxepin

    go.drugbank.com/drugs/DB01142
    ApprovedInvestigational

    [T559] It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to [cidoxepin]. Doxepin commonly produces a 5:1 (E):(Z) racemic mixture. … Doxepin is a psychotropic agent with antidepressant and anxiolytic properties.

    Categories: Adrenergic alpha-1 Receptor Antagonists, Heterocyclic Compounds, 1-RingProducts: Rho-doxepin-10 Mg Cap, APO-DOXEPIN CAPSULE 10 mg
  8. Drug

    Metoprolol

    go.drugbank.com/drugs/DB00264
    ApprovedInvestigational

    Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. … [A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527]

    Synonyms: 1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-olMixtures: Implicor 50 mg/5 mg Filmtabletten, IMPLICOR FILM-COATED TABLET 50 mg/5 mg
  9. Drug

    Ascorbic acid

    go.drugbank.com/drugs/DB00126
    ApprovedInvestigationalNutraceutical

    Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant. … A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables.

    Synonyms: Vitamin C, Vitamin-CMixtures: DAYCOLD-HOT 500/10/15/100 MG SAŞE ,10 SAŞE, DAYCOLD-HOT 500/10/15/100 MG SAŞE,6 SAŞE
  10. Drug

    Pentoxifylline

    go.drugbank.com/drugs/DB00806
    ApprovedInvestigational

    Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties. … [A226410, A226415, A226455] More recently, PTX has been suggested as a possible treatment for COVID-19-induced pulmonary complications due to its ability to regulate the production of inflammatory cytokines

    Mixtures: Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5%Categories: Phosphodiesterase 5 Inhibitors, Cytochrome P-450 Substrates