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Displaying results 2171 - 2180 of 10000 in total
  1. Drug

    Rosomidnar

    go.drugbank.com/drugs/DB17154
    Investigational

    Synonyms: (3'-5')d(c-a-c-g-c-a-c-g-c-g-c-a-t-c-c-c-c-g-c-c-c-g-t-g)
  2. Drug

    Navtemadlin

    go.drugbank.com/drugs/DB15299
    Investigational

    Navtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and Decitabine in Treating Patients With Relapsed, Refractory, or Newly-Diagnosed Acute Myeloid Leukemia

    Categories: Heterocyclic Compounds, 1-RingSynonyms: {(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-[ (2S)-3 -methyl-1-(propan-2- ylsulfonyl)butan-2-yl]-2-oxopiperidin-3-yl}acetic acid
  3. Drug

    MRK-003

    go.drugbank.com/drugs/DB17015
    Experimental

    MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of [MK-0752], a drug in clinical development.[A252682]

    Synonyms: (1'R,4R)-2-(2,2,2-trifluoroethyl)-5'-[(E)-3-[4-(trifluoromethyl)piperidin-1-yl]prop-1-enyl]spiro[1,2,5-thiadiazolidine-4,13'-tricyclo[8.2.1.03,8]trideca-3(8),4,6-triene] 1,1-dioxideCategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    OP-145

    go.drugbank.com/drugs/DB05672
    Experimental

    OP-145 is a synthetic antimicrobial peptide developed from human cathelicidin LL-37.

    Synonyms: (4S)-4-(((2S)-2-((2-(((2S,3S)-2-ACETAMIDO-3-METHYL-PENTANOYL)AMINO)ACETYL)AMINO)-6-AMINO-HEXANOYL)AMINO)-5-(((1S)-2-(((1S)-5-AMINO-1-(((1S)-1-(((1S,2S)-1-(((1S)-1-(((1S)-1-(((1S)-1-(((1S,2S)-1-(((1S)-5, -AMINO-1-(((1S)-1-(((1S)-1-BENZYL-2-(((1S)-1-(((1S)-1
  5. Drug

    Ocifisertib

    go.drugbank.com/drugs/DB18746
    Investigational

    Synonyms: (1R,2S)-2-{3-[(E)-2-(4-{[(2R,6S)-2,6-dimethylmorpholin-4-yl]methyl}phenyl)ethen-1-yl]-1Hindazol-6-yl}-5'-methoxyspiro[cyclopropane-1,3'-indol]-2'(1'H)-one, (1R,2S)-2-[3-[(1E)-2-[4-[[(2R,6S)-2,6-Dimethyl-4-morpholinyl]methyl]phenyl]ethenyl]-1H-indazol-6-yl]-5′-methoxyspiro[cyclopropane-1,3′-[3H]indol]-2′(1′H)-oneCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  6. Drug

    INCB-086550

    go.drugbank.com/drugs/DB18901
    Investigational

    INCB-086550 is under investigation in clinical trial NCT04629339 (Study of INCB086550 in Select Solid Tumors).

    Synonyms: 3-PYRROLIDINECARBOXYLIC ACID, 1-((7-CYANO-2-(3'-((3-(((3R)-3-HYDROXY-1-PYRROLIDINYL)METHYL)-1,7-NAPHTHYRIDIN-8-YL)AMINO)-2,2'-DIMETHYL(1,1'-BIPHENYL)-3-YL)-5-BENZOXAZOLYL)METHYL)-, (3R)-
  7. Drug

    9-Amino-2-deoxy-2,3-dehydro-n-acetyl-neuraminic acid

    go.drugbank.com/drugs/DB04227
    Experimental

    Synonyms: 9-Amino-2-deoxy-2,3-dehydro-n-acetyl-neuraminic acid, (6R)-5-Acetamido-6-[(1R,2R)-3-amino-1,2-dihydroxypropyl]-2,6-anhydro-3,5-dideoxy-L-threo-hex-2-enonic acid
  8. Drug

    Atilotrelvir

    go.drugbank.com/drugs/DB19439
    Investigational

    Atilotrelvir is under investigation in clinical trial NCT05041907 (Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV)).

    Synonyms: (1R,4S,6S)-N-{(1S)-1-ciano-2-[(3S)-2-oxopirrolidin-3-il]etil}-5-[(2S)-3,3-dimetil-2-(2,2,2-trifluoroacetamido)butanoil]-5-azaespiro[biciclo[2.2.1]heptano-2,1'-ciclopropano]-6-carboxamida, Spiro[2-azabicyclo[2.2.1]heptane-5,1′-cyclopropane]-3-carboxamide, N-[(1S)-1-cyano-2-[(3S)-2-oxo-3-pyrrolidinyl]ethyl]-2-[(2S)-3,3-dimethyl-1-oxo-2-[(2,2,2-trifluoroacetyl)amino]butyl]-, (1S,3S,4R)-
  9. Drug

    Tigozertinib

    go.drugbank.com/drugs/DB19239
    Investigational

    Tigozertinib (BLU-945) is currently under investigation in clinical trial NCT04862780 (Phase 1/​2 Study Targeting EGFR Resistance Mechanisms in NSCLC) for the treatment of NSCLC.

    Synonyms: 3-ISOQUINOLINAMINE, N-(2-((3S,4R)-3-FLUORO-4-METHOXY-1-PIPERIDINYL)-4-PYRIMIDINYL)-5-(1-METHYLETHYL)-8-((2R,3S)-2-METHYL-3-((METHYLSULFONYL)METHYL)-1-AZETIDINYL)-, N-{2-[(3S,4R)-3-fluoro-4-methoxypiperidin-1-yl]pyrimidin-4-yl}-5-(propan-2-yl)-8-[(2R,3S)-2-methyl-3-[(methanesulfonyl)methyl]azetidin-1-yl]isoquinolin-3-amine
  10. Drug

    Tomligisiran

    go.drugbank.com/drugs/DB19330
    Investigational

    Tomligisiran is under investigation in clinical trial NCT06537414 (A Study of Sequential Therapy With Daplusiran/tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis … B (CHB)).

    Synonyms: RNA, ((1'-DE(6-AMINO-9H-PURIN-9-YL))DA-(5'->5')-CM-GM-CM-UM-GM-UM-AM-GM-(2'-DEOXY-2'-FLUORO)G-(2'-DEOXY-2'-FLUORO)C-(2'-DEOXY-2'-FLUORO)A-UM-AM-AM-AM-UM-UM-GM-GM-UM-AM-(3'->3')-SP-(1'-DE(6-AMINO-9H-PURIN, -9-YL))DA), 3'-(O-(CIS-4-((3S,8S)-17-((2-(ACETYLAMI