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Aminoglutethimide
go.drugbank.com/drugs/DB00357ApprovedWithdrawnIt was formerly used for its weak anticonvulsant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p454)
Thiram
go.drugbank.com/drugs/DB13245ApprovedThiram is mainly used as a fungicide for plants and treatment for seeds, however, this use is being investigated for safety in many markets including Canada [L5425].
Categories: Compounds used in a research, industrial, or household settingDotatate gallium Ga-68
go.drugbank.com/drugs/DB13925ApprovedInvestigationalWithdrawnGa-68 dotatate has a high affinity for somatostatin-2 receptor and it is rapidly excreted from the nontarget sites which gives it an ideal candidate for imaging neuroendocrine tumors.
Nomegestrol acetate
go.drugbank.com/drugs/DB13981ApprovedNomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
Categories: Hormonal Contraceptives for Systemic UseSynonyms: 17-alpha-Acetoxy-6-methyl-19-nor-4,6-pregnadiene-3,20-dioneCeruletide
go.drugbank.com/drugs/DB00403ApprovedCaerulein is a specific decapeptide similar in action and composition to the natural gastrointestinal peptide hormone cholecystokinin. It exerts stimulatory effects on the gastric, biliary, and pancreatic secretion, as well as on certain...
Categories: Tests for Bile Duct PatencyEluxadoline
go.drugbank.com/drugs/DB09272ApprovedInvestigationalEluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D). … Agonism of peripheral mu-opioid receptors results in reduced colonic motility, while antagonism of central delta-opioid receptors results in improved analgesia, making eluxadoline usable for the symptoms
Cefroxadine
go.drugbank.com/drugs/DB11367ApprovedWithdrawnCefroxadine is an orally available cephalosporin antibiotic. As part of its drug class, it shares structural properties to cefalexin as well as its activity spectrum. It was used in Italy but has since been withdrawn.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseVericiguat
go.drugbank.com/drugs/DB15456ApprovedInvestigational[L31178] Vericiguat was approved by the FDA in January 2021 - developed by Merck under the brand name Verquvo - for use in certain patients with systolic heart failure. … to its structure have dramatically decreased its susceptibility to oxidative metabolism,[A227458] resulting in a relatively long half-life and allowing for once-daily dosing.
Tinidazole
go.drugbank.com/drugs/DB00911ApprovedInvestigationalA nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: TINIDAZOL TABLETAS POR 500 MG, REZOL TABLETA RECUBIERTA POR 1G.Technetium Tc-99m succimer
go.drugbank.com/drugs/DB09436Approved[L40558] The use of technetium Tc-99m succimer for the detection of kidney cortical defects was first approved by the FDA on February 23, 2022, under the market name NephroScan.[L40573] … Technetium Tc-99m succimer is used with gamma scintigraphy or single-photon emission computed tomography (SPECT).
Categories: Compounds used in a research, industrial, or household setting