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Pyrimethamine
go.drugbank.com/drugs/DB00205ApprovedInvestigationalVet approvedOne of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Milrinone
go.drugbank.com/drugs/DB00235ApprovedInvestigationalOften the result of long-term myocardial ischemia, cardiomyopathy, or other cardiac insults, heart failure results from an inability of the heart to perfuse peripheral tissues with sufficient oxygen and … [A228333] As a PDE-III inhibitor, milrinone results in increased cAMP levels and improves cardiac function and peripheral vasodilation in acute decongested heart failure.
Categories: Compounds used in a research, industrial, or household settingProducts: MILRICOR 10MG/10ML IV ENJEKSIYON / INFÜZYON IÇIN ÇÖZELTI IÇEREN AMPUL, 1 ADET, KARDIYOMIL 10 MG/10 ML IV ENJEKSIYON/INFÜZYON IÇIN ÇÖZELTI IÇEREN AMPUL ,1 ADETMethimazole
go.drugbank.com/drugs/DB00763ApprovedInvestigationalpro-drug [carbimazole], which is an antithyroid medication used in the United Kingdom and parts of the former British Commonwealth. … [A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949[A184502] and is now commonly used in the management of hyperthyroidism, particularly in those for whom more aggressive
Products: THYROMAZOL 5MG TABLET, 30 ADET, THYROMAZOL 5MG TABLET, 50 ADETTafenoquine
go.drugbank.com/drugs/DB06608ApprovedInvestigationalTafenoquine is an 8-aminoquinoline analogue of primaquine which varies only on the presence of a 5-phenoxy group. … [A35671, A35690] It was discovered by the scientists at the Walter Reed Army Institute of Research in 1978 as a substitute for primaquine that would be more effective against relapsing vivax malaria.
Nipocalimab
go.drugbank.com/drugs/DB16257ApprovedInvestigational[L64042] It is an aglycosylated, fully human IgG1 monoclonal antibody that binds FcRn and blocks the receptor's recycling of immunoglobulin G (IgG), thereby lowering circulating IgG levels, including pathogenic … Nipocalimab-aahu is a neonatal Fc receptor (FcRn) blocker used to treat certain antibody-mediated autoimmune diseases.
Synonyms: immunoglobulin G1-lambda, anti-[Homo sapiens FCGRT (Fc fragment of IgG receptor and transporter, neonatal Fc receptor, FcRn, transmembrane alpha chain of the neonatal receptor)], Homo sapiens monoclonalIproclozide
go.drugbank.com/drugs/DB09247ApprovedWithdrawnAlthough it was employed as an antidepressant for a time, the fact that the agent is capable of causing fulminant hepatitis and that its use has been documented as the cause for at least three reported … Iproclozide is an irreversible and selective hydrazine class based monoamine oxidase inhibitor (MAOI).
Tibolone
go.drugbank.com/drugs/DB09070ApprovedInvestigationalTibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha [L1874]. … In June 2006, Organon Pharmaceuticals announced the receipt of a Not Approvable Letter from the U.S.
Categories: Sex Hormones and Modulators of the Genital SystemProducts: LADYBON 2.5 MG TABLET, 28 ADET, LIVIAL 2.5 MG TABLET, 84 ADETThymol
go.drugbank.com/drugs/DB02513ApprovedInvestigationalA phenol obtained from thyme oil or other volatile oils. It is used as a stabilizer in pharmaceutic preparations. … It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a vermifuge. (Dorland, 28th ed)
Mixtures: GLYCERIN OF THYMOL, Mastic DentProducts: Acne Vanish Synergy for treatment of AcnesTechnetium Tc-99m disofenin
go.drugbank.com/drugs/DB09164ApprovedWithdrawnIt is available as an intravenous injection in a preparation kit under the name Hepatolite. … Technetium Tc-99m is a metastable nuclear isomer and disofenin is an iminodiacetic acid derivative with no known pharmacologic actions at the doses recommended.
Categories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of ChemicalsProducts: Kit for the Preparation of Technetium Tc99m DisofeninDyclonine
go.drugbank.com/drugs/DB00645ApprovedInvestigationalDyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. It may also be found in some Cepacol sore throat spray products.