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Paclitaxel
go.drugbank.com/drugs/DB01229ApprovedInvestigationalVet approvedUsed as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel … It is available as an intravenous solution for injection and the newer formulation contains albumin-bound paclitaxel marketed under the brand name Abraxane.
Synonyms: 5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserineProducts: PLACLITAX®INY, SINDAXEL 300 MG/50 ML IV INF. KONSANTRE COZ. ICEREN FLAKON, 1 ADETGlatiramer
go.drugbank.com/drugs/DB05259ApprovedInvestigational[A248880] It was approved by the FDA in 1996, and a generic version became available in 2017. … [A248870] Originally, glatiramer acetate was designed as a stimulant of myelin basic protein (MBP), a myelin antigen involved in the development of multiple sclerosis (MS), to induce experimental autoimmune
Synonyms: Copolymer I (synthetic peptide)Products: Copaxone 20 mg/ml Injektionslösung in einer Fertigspritze, Copaxone 40 mg/ml Injektionslösung in einer FertigspritzeSodium bicarbonate
go.drugbank.com/drugs/DB01390ApprovedInvestigationalSodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Mixtures: E-Z-gas II, Iris Ink Eye DropsProducts: SAL DE FRUTAS LUA II, Sodium Bicarbonate Inj 4.2%Urokinase
go.drugbank.com/drugs/DB00013ApprovedInvestigationalWithdrawnUrokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase. … [A191943] Urokinase was granted FDA approval on 16 January 1978.[L12138]
Products: UROKINASE-GREEN CROSS INJ. 60,000 iu/vial, UROKINASE KGCC INJ. 250000 IU FLAKON, 1 ADETIncrease in Intracranial Pressure (ICP)
go.drugbank.com/conditions/DBCOND0113421Synonyms: Increase in Intracranial Pressure (ICP)Leydig Cell Failure in Adult
go.drugbank.com/conditions/DBCOND0081825Drugs: MesteroloneSynonyms: Leydig Cell Failure in Adult, Leydig cell failure in adult (disorder)Burning sensation in the mouth
go.drugbank.com/conditions/DBCOND0102063Drugs: Benzoic acidSynonyms: Discomfort in mouth, Burning sensation in the mouthDeficiencies in enzymes of the urea cycle
go.drugbank.com/conditions/DBCOND0023710Drugs: Phenylbutyric acidSynonyms: Deficiencies in enzymes of the urea cycleIcatibant
go.drugbank.com/drugs/DB06196ApprovedInvestigationalswelling, thus demonstrating bradykinin involvement in the disease pathophysiology. … [A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema.
Categories: Drugs Used in Hereditary AngioedemaProducts: Icatibant STADA 30 mg Injektionslösung in einer Fertigspritze, Icatibant Hikma 30 mg Injektionslösung in einer FertigspritzeKetamine
go.drugbank.com/drugs/DB01221ApprovedInvestigationalVet approvedIt started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic effects. … Ketamine is an NMDA receptor antagonist with a potent anesthetic effect.[A31869] It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories.
Categories: N-Methylaspartate, agonists, N-Methylaspartate, antagonists & inhibitorsProducts: Ketamin G.L. 10 mg/ml - Injektions-/Infusionslösung in Ampullen, Ketamin G.L. 50 mg/ml - Injektions-/Infusionslösung in Ampullen