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Tramadol
go.drugbank.com/drugs/DB00193ApprovedInvestigationalIt is considered a Step 2 option on the World Health Organization's pain ladder and has about 1/10th of the potency of [morphine]. … Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain.
Mixtures: ONEMER DT, DOLAC DUOCategories: Combined Inhibitors of Serotonin/Norepinephrine Reuptake, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeClarithromycin
go.drugbank.com/drugs/DB01211ApprovedInvestigationalClarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration.
Categories: Metabolic Side Effects of Drugs and SubstancesSynonyms: 6-O-methyl erythromycin, 6-O-methylerythromycinMupirocin
go.drugbank.com/drugs/DB00410ApprovedInvestigationalVet approvedDue to its unique mode of action of inhibiting the activity of bacterial isoleucyl-tRNA synthetase, mupirocin does not demonstrate cross-resistance with other classes of antimicrobial agents, giving it … [L10580] It is available in topical formulations only due to extensive systemic metabolism[A178531] and is used in the treatment of impetigo caused by _Staphylococcus aureus_ and _Streptococcus pyogenes
Products: Sx Pre-Op Prep PouchPentaerythritol tetranitrate
go.drugbank.com/drugs/DB06154ApprovedWithdrawnIt is also one of the most powerful high explosives known and is a component of the plastic explosive known as Semtex [L2393]. PETN has the chemical formula C5H8N4O12. … It is a vasodilator with properties that are quite similar to those of glyceryl trinitrate, however, with a more prolonged duration of action.
Synonyms: PENT, Tetranitrato de pentaeritritiloCategories: Vasodilators Used in Cardiac DiseasesChloramphenicol
go.drugbank.com/drugs/DB00446ApprovedInvestigationalVet approvedWithdrawnspecific route of administration. … (From Martindale, The Extra Pharmacopoeia, 29th ed, p106) The FDA has withdrawn all oral drug products containing chloramphenicol, due to the high risk of fatal aplastic anemia associated with this
Mixtures: CLOXONA-O, Ophthocort OntCategories: Antiinfectives for Treatment of AcneOxymetazoline
go.drugbank.com/drugs/DB00935ApprovedInvestigational[L15057] In July 2020, the FDA approved the use of an ophthalmic formulation of oxymetazoline (Upneeq) in adults with acquired blepharoptosis, or ptosis, making it the first FDA-approved medical treatment … [A215542] Oxymetazoline is available in various formulations with a wide variety of clinical implications. The topical formulation of the drug is used to treat persistent facial redness in adults.
Mixtures: N-S-4Products: Sudafed OM, Nasal DChlortetracycline
go.drugbank.com/drugs/DB09093ApprovedVet approvedWithdrawnHe discovered that this antibiotic was the product of an actinomycete strain he cultured and obtained from a soil sample from a field in Missouri. … The organism was named _Streptomyces aureofaciens_ due to its gold-hued color.
Categories: combinations of tetracyclinesProducts: Aureomycin Ont 3%, Aureomycin Ont Oph 1%Hydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approved[A188420] Hydrocortisone was granted FDA approval on 5 August 1952.[L10574] … [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone.
Mixtures: Ti-U-lac HC Lotion, DESYN-NCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseSodium chloride
go.drugbank.com/drugs/DB09153ApprovedInvestigationalVet approvedSodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines. … Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions.
Mixtures: OQ-BALANS, OQ-BALANSProducts: Of Nacl .9%, BIO NASAL O.9%Colistimethate
go.drugbank.com/drugs/DB01111ApprovedInvestigationalVet approvedColistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa. … Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms.
Products: Colomycin Injection 1 million International Units, POWDER FOR SOLUTION FOR INJECTION, INFUSION, OR INHALATION, COLIMYCIN 1.150.000 IU IM/IV ENJEKSIYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 1 ADET