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Methoxyflurane
go.drugbank.com/drugs/DB01028ApprovedInvestigationalVet approvedWithdrawnIf so employed, it should be administered with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular … (From AMA Drug Evaluations Annual, 1994, p180) In the US, methoxyflurane is one of the products that have been withdrawn or removed from the market for reasons of safety or effectiveness.[L43942]
Dydrogesterone
go.drugbank.com/drugs/DB00378ApprovedInvestigationalWithdrawnA synthetic progestational hormone with no androgenic or estrogenic properties. … Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.
Sickle Cell Disease
go.drugbank.com/conditions/DBCOND0029334Synonyms: Sickling Disorder Due to Hemoglobin S, Sickling disorder due to hemoglobin S (disorder)Imipramine
go.drugbank.com/drugs/DB00458ApprovedInvestigationalImipramine may be used to treat depression and nocturnal enuresis in children [FDA Label]. … TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring.
Synonyms: 10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine, N-(γ-dimethylaminopropyl)iminodibenzylCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeRibociclib
go.drugbank.com/drugs/DB11730ApprovedInvestigationalThese proteins, when over-activated, can enable cancer cells to grow and divide too quickly. Ribociclib was approved by the FDA in March 2017 under the brand name Kisqali. … Ribociclib is a selective cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and 6 (CDK4/6).
Mixtures: Kisqali Femara Co-pack, Kisqali Femara Co-packNonacog beta pegol
go.drugbank.com/drugs/DB13933ApprovedInvestigationalOnce activated, the activation molecule with PEG is cleaved to leave the activated factor IX (Factor IXa). … [A31496] Nonacog beta pegol was developed by Novo Nordisk and received its first global approval by the FDA on May 31, 2017,[L1098] followed by the European Commission approval on June 2, 2017.
Sodium citrate
go.drugbank.com/drugs/DB09154ApprovedInvestigationalFrom the medical point of view, it is used as alkalinizing agent. It works by neutralizing excess acid in the blood and urine. It has been indicated for the treatment of metabolic acidosis.
Mixtures: N-ORS Oral Rehydration Salts (Orange Flavour), LITORAL TOZ, 2 ADETRosin
go.drugbank.com/drugs/DB11165ApprovedRosin is a solid form of resin obtained from pines and other plants, mostly conifers. It is prepared from heating fresh liquid resin to vaporize the volatile liquid terpene components. … Rosin has shown to mediate antibacterial actions on Gram-positive bacterial species [A27267].
Vonicog alfa
go.drugbank.com/drugs/DB12872ApprovedInvestigationalVonicog alfa is a recombinant human von Willebrand factor (rVWF) produced from Chinese hamster ovary cells. … [A264389] Vonicog alfa works to reduce bleeding events and bleeding times in patients with vWD, who have deficiencies in VWF.[A264389]
Synonyms: (618-THREONINE,709-ASPARTIC ACID)VON WILLEBRAND FACTOR HOMO SAPIENS (1381A>T,1472H>D VARIANT) BLOOD COAGULATION FACTORDehydroascorbic acid
go.drugbank.com/drugs/DB08830ExperimentalDehydroascorbic acid is made from the oxidation of ascorbic acid. This reaction is reversible, but dehydroascorbic acid can instead undergo irreversible hydrolysis to 2,3-diketogulonic acid. … Currently dehydroascorbic acid is an experimental drug with no known approved indications.