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Displaying results 2211 - 2220 of 10000 in total
  1. Drug

    Vilastobart

    go.drugbank.com/drugs/DB19327
    Investigational

    Vilastobart is under investigation in clinical trial NCT04896697 (Vilastobart (XTX101) Monotherapy and Vilastobart and Atezolizumab Combination Therapy in Advanced Solid Tumors).

    Synonyms: G1v7 CH2 D3, E117 (CH1 K120 (216) (120-217), hinge 1-, gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV1-69*08 (84.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT[8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, D12, L14,
  2. Drug

    13-deoxydoxorubicin

    go.drugbank.com/drugs/DB05706
    Investigational

    GPX-100 is an anthracycline anticancer drug that belongs to the family of drugs called antitumor antibiotics.

  3. Drug

    Lanolin

    go.drugbank.com/drugs/DB11112
    Approved

    Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid [L2580].

    Mixtures: Dg Baby Vitamins A and D, Good Neighbor Pharmacy Vitamin A and DCategories: Compounds used in a research, industrial, or household setting
  4. Drug

    Merbromin

    go.drugbank.com/drugs/DB13392
    Investigational

    It is an organomercuric disodium salt compound and a fluorescein that is available in many countries, except Switzerland, France, Germany, and the United States where the drug was withdrawn from market … Mercurochrome is a trade name of merbromin commonly used as a topical first-aid antiseptic agent.

    Products: BERKOMER SOLUSYON, 50 ML, MERBROMINA NA
  5. Drug

    Tipiracil

    go.drugbank.com/drugs/DB09343
    ApprovedInvestigational

    Tipiracil is a thymidine phosphorylase inhibitor. It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. … The main function of Tipiracil in TAS-102 is to increase trifluridine bioavailability by inhibiting its catabolism.

    Mixtures: LONSURF FILM-COATED TABLET 15 MG/6.14 MG, LONSURF FILM-COATED TABLET 15 MG/6.14 MGCategories: MATE 1 Substrates with a Narrow Therapeutic Index, OCT2 Substrates with a Narrow Therapeutic Index
  6. Drug

    Procainamide

    go.drugbank.com/drugs/DB01035
    Approved

    A derivative of procaine with less CNS action.

    Categories: Antiarrhythmics, Class Ia, OCT2 Substrates with a Narrow Therapeutic IndexProducts: Pronestyl Inj 100mg/ml, Procainamide-500 Cap 500mg
  7. Drug

    Lorcaserin

    go.drugbank.com/drugs/DB04871
    ApprovedInvestigationalWithdrawn

    In February 2020, the FDA issued a Drug Safety Communication requesting the manufacturer of Belviq (lorcaserin hydrochloride tablets, 10 mg) and Belviq XR (lorcaserin hydrochloride extended-release tablets … , 20 mg) to voluntarily withdraw these products from the U.S. market, and the company has submitted a request to voluntarily withdraw the drug.

  8. Target

    Galectin-10

    go.drugbank.com/bio_entities/BE0001886
    TargetHumans

    Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg)

    Polypeptides: Galectin-10Synonyms: Gal-10
  9. Target

    Frizzled-10

    go.drugbank.com/bio_entities/BE0020969
    TargetHumans

    Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclea...

    Polypeptides: Frizzled-10Synonyms: Fz-10
  10. Target

    Interleukin-10

    go.drugbank.com/bio_entities/BE0002484
    TargetHumans

    Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetram...

    Polypeptides: Interleukin-10Synonyms: IL-10