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Cinitapride
go.drugbank.com/drugs/DB08810InvestigationalCinitapride is a gastroprokinetic agent and antiulcer benzamide with agonist activity at 5-HT1 and 5-HT4 receptors and antagonist activity at 5-HT2 receptors. It is marketed in Spain and Mexico.
Mixtures: ROGASTRIL PLUS®, ROGASTRIL PLUS®Categories: Serotonin 5-HT1 Receptor Agonists, Serotonin 5-HT2 Receptor AntagonistsHyaluronic acid
go.drugbank.com/drugs/DB08818ApprovedInvestigationalVet approvedA popular use of hyaluronic acid in recent years is cosmetic injection due to its ability to minimize the appearance of wrinkles and aging-related skin imperfections.[L32193]
Mixtures: Vitamin C 15% (L- Ascorbic Acid), Vitamin C 25% (L- Ascorbic Acid)Categories: Compounds used in a research, industrial, or household settingIvacaftor
go.drugbank.com/drugs/DB08820ApprovedInvestigational[L6841] Ivacaftor is administered as a monotherapy and also administered in combination with other drugs for the management of CF. … Ivacaftor (also known as Kalydeco or VX-770) is a drug used for the management of Cystic Fibrosis (CF). It is manufactured and distributed by Vertex Pharmaceuticals.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamideDeferiprone
go.drugbank.com/drugs/DB08826ApprovedInvestigationalThalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired. … Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 1,2-Dimethyl-3-hydroxypyrid-4-one, 3-Hydroxy-1,2-dimethyl-4(1H)-pyridoneDehydroascorbic acid
go.drugbank.com/drugs/DB08830ExperimentalDehydroascorbic acid as well as ascorbic acid are both termed Vitamin C, but the latter is the main form found in humans.
Categories: Vitamin C and analoguesSynonyms: L-threo-2,3-hexodiulosonic acid, γ-lactone, L-dehydroascorbate2-deoxyglucose
go.drugbank.com/drugs/DB08831InvestigationalAlthough there are several possible therapeutic indications for 2-deoxyglucose, presently there is no approved indication for 2-deoxyglucose as a therapeutic agent. … 2-deoxyglucose is predominantly used as a diagnostic agent in its radiolabelled form (fluorine-18 is used as the radiolabel).
Synonyms: 2-deoxy-D-glucose, 2-Deoxy-D-arabino-hexoseTaurochenodeoxycholic acid
go.drugbank.com/drugs/DB08833ExperimentalAs a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely used as a choleretic to increase the volume of bile secretion from the liver and as a cholagogue to
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTauroursodeoxycholic acid
go.drugbank.com/drugs/DB08834ApprovedInvestigationalWithdrawnTauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid [A249070] that is produced in humans at a low concentration. … [A249070] It is a taurine conjugate of [ursodeoxycholic acid] [A249065] with comparable therapeutic efficacy and safety,[A249070] but a much higher hydrophilicity.
Agmatine
go.drugbank.com/drugs/DB08838ExperimentalAgmantine is a natural metabolite of the amino acid arginine. … As an investigational drug, it is being studied in a non-blinded prospective case study in the United States looking at patients who have been diagnosed with small fiber peripheral neuropathy between the
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 1-amino-4-guanidobutane, N-(4-aminobutyl)guanidineTyramine
go.drugbank.com/drugs/DB08841InvestigationalNutraceuticalTyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine.