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Cenegermin
go.drugbank.com/drugs/DB13926ApprovedInvestigationalsignificant improvement in the safety or effectiveness of the treatment, diagnosis or prevention of a serious condition. … The approval of cenegermin consequently provides a novel topical treatment that has the potential capacity to offer total corneal healing for many patients who may use the agent.
Hydroxocobalamin
go.drugbank.com/drugs/DB00200ApprovedInvestigationalHydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. It is also used in cyanide poisoning, Leber's optic atrophy, an...
Mixtures: TRIBEDOCE C/LCategories: Heterocyclic Compounds with 4 or More RingsPraziquantel
go.drugbank.com/drugs/DB01058ApprovedInvestigationalVet approvedPraziquantel is a pyrazino-isoquinolein derivative from the thioxantonic group used as a broad anthelmintic spectrum. … Specifically, it is known as a treatment of trematodes and cestodes infections such as schistosomiasis, taeniasis, and cysticercosis.
Mixtures: Eqvalan Duo Oral Paste for HorseChlorpropamide
go.drugbank.com/drugs/DB00672ApprovedWithdrawnChlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). … Chlorpropamide is not recommended for the treatment of NIDDM as it increases blood pressure and the risk of retinopathy (UKPDS-33).
Zunsemetinib
go.drugbank.com/drugs/DB16502InvestigationalZunsemetinib is being investigated in a new clinical trial (NCT06374459) for the treatment of hormone receptor-positive and HER2-negative metastatic breast cancer with bone metastasis. … Additionally, ATI-450 was studied in a terminated trial (NCT05511519) to treat patients with psoriatic arthritis.
Categories: Experimental Unapproved Treatments for COVID-19Procaine benzylpenicillin
go.drugbank.com/drugs/DB09320ApprovedVet approvedBenzylpenicillin is active against a wide range of organisms and is the drug of first choice for many infections. … It is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and the local anaesthetic agent procaine in equimolar amounts.
Mixtures: Bicillin A-P Injection PwsCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseGuselkumab
go.drugbank.com/drugs/DB11834ApprovedInvestigationalGuselkumab is a human immunoglobulin G1 lambda (IgG1λ) monoclonal antibody that selectively blocks interleukin-23. … Developed by Janssen, the subcutenous injection form of guselkumab was approved in July 2017 under the market name Tremfya for the treatment of adult patients with moderate-to-severe plaque psoriasis.
Products: TREMFYA 100MG/ML SOLUTION FOR INJECTION, Tremfya One-Press 100mg/ml Solution for InjectionCentanafadine
go.drugbank.com/drugs/DB14841ApprovedInvestigationalage or weight. … Centanafadine is a reuptake inhibitor at the norepinephrine, dopamine, and serotonin transporters and a central nervous system stimulant.
Categories: Psychostimulants, Agents Used for ADHD and NootropicsFlupirtine
go.drugbank.com/drugs/DB06623InvestigationalFlupirtine is a pyridine derivative that is in clinical use as a nonopioid analgesic. It was approved for the treatment of pain in 1984 in Europe. … It is not approved for use in the U.S. or Canada, but is currently in phase II trials for the treatment of fibromyalgia.
Amphotericin B
go.drugbank.com/drugs/DB00681ApprovedInvestigationalAmphotericin B shows a high order of in vitro activity against many species of fungi. … While Candida albicans is generally quite susceptible to amphotericin B, non-albicans species may be less susceptible. Pseudallescheria boydii and Fusarium sp. are often resistant to amphotericin B.
Categories: Compounds used in a research, industrial, or household setting, Antimycotics for Systemic UseProducts: L- AMPHOSEVEN 50, AMPHOTRET FOR INJECTION USP 50MG