Search

Displaying results 2231 - 2240 of 10000 in total
  1. Drug

    Ustekinumab

    go.drugbank.com/drugs/DB05679
    ApprovedInvestigational

    Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses. … [A187346] The therapeutic use of the drug started in Canada, the US, and Europe since 2009 when it was first approved for the treatment of adult patients with moderate to severe plaque psoriasis and

    Products: Stelara Solution for Injection in Pre-Filled Syringe 90 mg/1 mL, Stelara Solution for Injection in Pre-Filled Syringe 45 mg/0.5mL
  2. Drug

    Norepinephrine

    go.drugbank.com/drugs/DB00368
    ApprovedInvestigational

    It is also found in plants and is used pharmacologically as a sympathomimetic. … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter.

    Synonyms: (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol, 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediolMixtures: XYLONOR %3 NORADRENALINE ENJEKSIYONLUK SOLUSYON ICEREN KULLANIMA HAZIR 50 KARTUS
  3. Drug

    Clindamycin

    go.drugbank.com/drugs/DB01190
    ApprovedInvestigationalVet approved

    The name lincomycin is derived from Lincoln, Nebraska, where it was first isolated from _Streptomyces lincolnensis_ found in a soil sample.[A190621] … Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris.

    Synonyms: 7(S)-Chloro-7-deoxylincomycin, Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranosideInternational brands: Dalacin C, Dalacin T Topical Solution
  4. Drug

    Bemiparin

    go.drugbank.com/drugs/DB09258
    ApprovedInvestigationalWithdrawn

    Like semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class [A7866]. … Interestingly, current research is underway for the potential benefit of bemiparin in the treatment of tumors and diabetic foot ulcers [L1468, A7866].

    Products: Ivor 2500 IE Anti-Xa/0,2 ml Injektionslösung in Fertigspritzen, HIBOR 2500 IU/0,2 ML KULLANIMA HAZIR 2 ENJEKTOR
  5. Drug

    AZD2315

    go.drugbank.com/drugs/DB06540
    Experimental

    The drug AZD2315, an immunosuppressant developed by AstraZeneca, was in Phase 1 clinical trials for the treatment of rheumatoid arthritis but was discontinued during this phase

    Synonyms: L-ALANINAMIDE, N-(1-OXO-5-PHENYLPENTYL)-L-ALANYL-L-ARGINYL-L-ALANYL-(.ALPHA.S,3R)-3-AMINO-.ALPHA.-METHYL-2-OXO-1-PYRROLIDINEACETYL-L-ALANYL-L-ARGINYL-N-(4-(2-AMINO-2-OXOETHYL)PHENYL)-, ACETATE (1:2), L-ALANINAMIDE, N-(1-OXO-5-PHENYLPENTYL)-L-ALANYL-L-ARGINYL-L-ALANYL-(.ALPHA.S,3R)-3-AMINO-.ALPHA.-METHYL-2-OXO-1-PYRROLIDINEACETYL-L-ALANYL-L-ARGINYL-N-(4-(2-AMINO-2-OXOETHYL)PHENYL)-, DIACETATE
  6. Drug

    Insulin glulisine

    go.drugbank.com/drugs/DB01309
    Approved

    Due to its duration of action of around 5 hours, Apidra is considered "bolus insulin" as it provides high levels of insulin in a short period of time to mimic the release of endogenous insulin from the … If left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening

    Categories: Drugs Used in Diabetes, Cytochrome P-450 CYP1A2 InducersProducts: APIDRA OPTIPEN 100 IU/ML SC KULLANIMI İÇİN ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, APIDRA 100 U/ML- SOLUTION FOR INJECTION IN VIAL
  7. Drug

    DYN-101

    go.drugbank.com/drugs/DB17921
    Investigational

    DYN-101 is an antisense product candidate designed to reduce the expression of dynamin 2 protein.

    Synonyms: 5’-cEtG-sp-cEt5MeU-sp-cEt5MeU-sp-dT-sp-dA-sp-dT-sp-dT-spdA-sp-dT-sp-dA-sp-dG-sp-dG-sp-dG-sp-cEt5MeC-sp-cEt5MeU-sp-cEt5MeU-3’
  8. Pathway

    Fatty Acid Elongation in Mitochondria

    smpdb.ca/view/SMP0000054
    Metabolic

    In liver and kidney fatty acid elongation operates best in the presence of both NADH and NADPH, whereas in heart and skeletal muscle, only NADH is required. … Mitochondrial elongation may result in fatty acids up to C16 in length. Fatty acid elongation in mitochondria is essentially the reverse of beta-oxidation for fatty acid oxidation.

    Drugs: NADH · Palmitic Acid
  9. Drug

    Sugammadex

    go.drugbank.com/drugs/DB06206
    ApprovedInvestigational

    Sugammadex (brand name Bridion) is marketed by Merck Sharp and Dohme, and was approved by the United States FDA on December 15, 2015. … Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery.

    Categories: Compounds used in a research, industrial, or household settingProducts: Sugammadex Aguettant 50 mg/ml Injektionslösung in einer Fertigspritze, BRIDION 500 MG/5 ML IV ENJEKSIYONLUK COZELTI ICEREN 10 FLAKON
  10. Drug

    PXL-770 free acid anhydrous

    go.drugbank.com/drugs/DB17615
    Experimental

    Synonyms: 2-chloro-3-(1-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl)-6-oxo- 5-phenyl-6,7-dihydrothieno(2, 3-b)pyridin-4-olateCategories: Heterocyclic Compounds, 1-Ring