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Displaying results 2261 - 2270 of 10000 in total
  1. Drug

    Luxeptinib

    go.drugbank.com/drugs/DB19179
    Investigational

    Synonyms: Urea, n-(4-(2,3-dihydro-7-(5-methyl-1h-imidazol-2-yl)-1-oxo-1h-isoindol-4-yl)-3-fluorophenyl)-n'-(2,4,6-trifluorophenyl)-, 32,72,74,76-tetrafluoro-14-methyl-21,23-dihydro-11h-4,6-diaza-2(4,7)-isoindola- 1(2)-imidazola-3(1,4),7(1)-dibenzenaheptaphane-2,35-dione
  2. Drug

    Nifedipine

    go.drugbank.com/drugs/DB01115
    ApprovedInvestigational

    Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to [nicardipine]. … [A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.

    Mixtures: NIF TEN 50, NIF-TEN CAPSULECategories: P-glycoprotein inducers, P-glycoprotein inhibitors
  3. Drug

    Enalapril

    go.drugbank.com/drugs/DB00584
    ApprovedInvestigationalVet approved

    It is also found in a combination product containing [hydrochlorothiazide] that is used for the management of hypertension. … Enalapril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor drug class that works on the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood

    Mixtures: DUOPRES® 5 MG / 20 MG CÁPSULAS, DUOPRES ® 5 MG / 10 MG CÁPSULASCategories: P-glycoprotein inhibitors, Agents Acting on the Renin-Angiotensin System
  4. Drug

    Desloratadine

    go.drugbank.com/drugs/DB00967
    ApprovedInvestigational

    Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. … It is the active descarboethoxy metabolite of loratidine (a second generation histamine).

    Mixtures: DESCASE 5 MG / 10 MG FILM KAPLI TABLET ,90 ADET, DESCASE 5 MG / 10 MG FILM KAPLI TABLET ,30 ADETCategories: P-glycoprotein inhibitors, Heterocyclic Compounds, 1-Ring
  5. Drug

    Ursodeoxycholic acid

    go.drugbank.com/drugs/DB01586
    ApprovedInvestigational

    [A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years. … [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by 7b-epimerization of [chenodeoxycholic acid], which is a primary bile acid.

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 Enzyme InducersSynonyms: (3α,5β,7β)-3,7-dihydroxycholan-24-oic acid
  6. Drug

    Rotenone

    go.drugbank.com/drugs/DB11457
    ExperimentalVet approved

    Rotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also toxic to fish.

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingSynonyms: 5'β-rotenone, [2R-(2α,6aα,12aα)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)[1]benzopyrano[3,4-b]furo[2,3-H][1]benzopyran-6(6aH)-one
  7. Drug

    Pheniramine

    go.drugbank.com/drugs/DB01620
    Approved

    Pheniramine is a first-generation antihistamine in the alkylamine class, similar to [brompheniramine] and [chlorpheniramine]. … [A181628] It is used in some over-the-counter allergy as well as cold & flu products in combination with other drugs.

    Mixtures: ANTIBEKSIN SURUP, 100 ML, OCTILIA ALLERGIA E INFIAMMAZIONECategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    IMT504

    go.drugbank.com/drugs/DB17792
    Investigational

    IMT504, a non-CpG 24-mer oligodeoxynucleotide, is an immunomodulatory oligonucleotide currently being investigated as a rabies vaccine.[A259467]

    Synonyms: DNA, D(P-THIO)(T-C-A-T-C-A-T-T-T-T-G-T-C-A-T-T-T-T-G-T-C-A-T-T), PyNTTTTGT class of oligodeoxynucleotide with a 24-base single chain composed of nucleotide sequence 5'TCATCATTTTGTCATTTTGTCATT 3'
  9. Drug

    Levosimendan

    go.drugbank.com/drugs/DB00922
    ApprovedInvestigationalWithdrawn

    Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels. … Levosimendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure).

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingProducts: SIMDAX 2.5 MG/ML KONSANTRE INF.COZ.5 ML X FLAKON, 1 ADET, LEVOSIMENDAN EG
  10. Drug

    Minnelide

    go.drugbank.com/drugs/DB17309
    Investigational

    Synonyms: Trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-c)furan-1(3h)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-8b-methyl-6a-(1-methylethyl)-6-((phosphonooxy)methoxy)-, sodium salt (1:2), (3bs,4as,5ar,6r,6as,7as,7bs,, 14-o-phosphonooxymethyltriptolide disodium salt