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Displaying results 221 - 230 of 10000 in total
  1. Drug

    Cilostazol

    go.drugbank.com/drugs/DB01166
    ApprovedInvestigational

    Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia … It is marketed under the brand name Pletal by Otsuka Pharmaceutical Co.. Cilostazol works by inhibiting both primary and secondary aggregation and reducing calcium-induced contractions.

    Synonyms: 3,4-dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone, 6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinoneCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  2. Drug

    Dextrose, unspecified form

    go.drugbank.com/drugs/DB09341
    ApprovedInvestigationalVet approved

    L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. … Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants.

    Mixtures: Normosol-R and Dextrose, Isolyte R In 5% DextroseCategories: Compounds used in a research, industrial, or household setting
  3. Drug

    Epirubicin

    go.drugbank.com/drugs/DB00445
    ApprovedInvestigational

    An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.

    Synonyms: (1S,3S)-3-GLYCOLOYL-1,2,3,4,6,11-HEXAHYDRO-3,5,12-TRIHYDROXY-10-METHOXY-6,11-DIOXO-1-NAPHTHACENYL 3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-ARABINO-HEXOPYRANOSIDE, 4'-EpiadriamycinCategories: Topoisomerase II Inhibitors, UGT2B7 Substrates with a Narrow Therapeutic Index
  4. Drug

    Tetracycline

    go.drugbank.com/drugs/DB00759
    ApprovedInvestigationalVet approvedWithdrawn

    Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. … The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: (4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
  5. Drug

    Belimumab

    go.drugbank.com/drugs/DB08879
    ApprovedInvestigational

    It is produced by recombinant DNA technology in a murine cell (NS0) expression system. … Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor.

    Categories: Decreased B Lymphocyte Activation, B Lymphocyte Stimulator-specific InhibitorProducts: BENLYSTIA SC, BENLYSTA 200 MG / 1 ML
  6. Drug

    Calcium lactate

    go.drugbank.com/drugs/DB13231
    ApprovedVet approved

    Calcium lactate is a salt that consists of two lactate anions for each calcium cation (Ca2+). … Calcium lactate is also found in daily dietary supplements as a source of calcium. It is also available in various hydrate forms, where calcium lactate pentahydrate is the most common.

    Synonyms: Calcium 2-hydroxypropanoate (1:2), Hemicalcium L-lactateMixtures: Cal M Tab, TOPPER-F TABLET
  7. Drug

    Neostigmine

    go.drugbank.com/drugs/DB01400
    ApprovedInvestigationalVet approved

    A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine.

    Synonyms: 3-Trimethylammoniumphenyl N,N-dimethylcarbamate, m-TrimethylammoniumphenyldimethylcarbamateProducts: NEOSTIGMIN 0,5 MG/ML IM/IV/SC ENJEKSİYONLUK ÇÖZELTİ, , 6 ADET, NEOSTİGMİN 0,5 MG/ML IM/IV/SC ENJEKSİYONLUK ÇÖZELTİ, , 50 ADET
  8. Drug

    Loteprednol etabonate

    go.drugbank.com/drugs/DB14596
    Approved

    Loteprednol Etabonate (LE) is a topical corticoid anti-inflammatory. … Moreover, LE was purposefully engineered to be a 'soft drug', one that is designed to be active locally at the site of administration and then rapidly metabolized to inactive components after eliciting

    Mixtures: TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET, LOTEMICIN®Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    Dextromethorphan

    go.drugbank.com/drugs/DB00514
    ApprovedInvestigational

    Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. … [A215412] Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]

    Mixtures: Bio-S-Pres DX, Sedilix-RX LinctusCategories: Uncompetitive N-methyl-D-aspartate Receptor Antagonist, Sigma-1 Agonist
  10. Drug

    Insulin glulisine

    go.drugbank.com/drugs/DB01309
    Approved

    Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. … Insulin is also used in the treatment of Type 2 Diabetes (T2D), another form of diabetes mellitus that is a slowly progressing metabolic disorder caused by a combination of genetic and lifestyle factors

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersProducts: APIDRA OPTIPEN 100 IU/ML SC KULLANIMI İÇİN ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, APIDRA ®