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Displaying results 221 - 230 of 10000 in total
  1. Drug

    Desipramine

    go.drugbank.com/drugs/DB01151
    Approved

    They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. … The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission.

    Categories: Tricyclics and Other Norepinephrine-reuptake InhibitorsSynonyms: N-(3-methylaminopropyl)iminobibenzyl
  2. Drug

    Prizloncabtagene autoleucel

    go.drugbank.com/drugs/DB18623
    Investigational

    C-CAR039 is an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific CAR.

    Synonyms: an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific CAR, targeting CD19 and CD20
  3. Drug

    Fluphenazine

    go.drugbank.com/drugs/DB00623
    Approved

    A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.

    Products: Moditen HCl Tab 10mg, Modecate Inj 25mg/ml
  4. Drug

    Tefidsogene civaparvovec

    go.drugbank.com/drugs/DB16789
    Investigational

    It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes … Developed by Sangamo Therapeutics, tefidsogene civaparvovec is being investigated in mucopolysaccharidosis type II.[A258789, L45949]

    Synonyms: NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/6 (RAAV REP2-CAP6) VECTOR, WHICH CONTAINS A PROMOTER-LESS HUMAN IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS EXONS 2-9 FROM HIDS AND
  5. Drug

    Glycerin

    go.drugbank.com/drugs/DB09462
    ApprovedInvestigational

    A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.

    Mixtures: Cry for You Lubricant Eye Drops, Up and Up HemorrhoidalCategories: Compounds used in a research, industrial, or household setting, Alimentary Tract and Metabolism
  6. Drug

    Epirubicin

    go.drugbank.com/drugs/DB00445
    ApprovedInvestigational

    An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.

    Categories: Anthracyclines and Related Substances, Antineoplastic and Immunomodulating AgentsProducts: PHARMORUBICIN CS 50MG/25ML, ANTHRACIN 50MG/25ML IV ENFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET
  7. Drug

    Infliximab

    go.drugbank.com/drugs/DB00065
    ApprovedInvestigational

    Infliximab was first approved by the FDA in 1998 under the market name Remicade as an intravenous injection. … Its hyperactivity and enhanced signalling pathways can be observed in inflammatory diseases where it activates further pro-inflammatory cascades.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: IMMUNOGLOBULIN G (HUMAN-MOUSE MONOCLONAL CA2 HEAVY CHAIN ANTI-HUMAN TUMOR NECROSIS FACTOR), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL CA2 LIGHT CHAIN, DIMER
  8. Drug

    Golimumab

    go.drugbank.com/drugs/DB06674
    ApprovedInvestigational

    Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with moderate to severe active rheumatoid arthritis (RA), (ii) alone or as an adjunct to methotrexate … Additionally in children and adolescents taking golimumab, there have been lymphoma and other malignancies observed.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: SIMPONI 100MG ILO IN FER, SIMPONI SOLUTION FOR INJECTION IN PRE-FILLED PEN 45MG/0.45ML
  9. Drug

    Adenosine

    go.drugbank.com/drugs/DB00640
    ApprovedInvestigational

    [A229828] Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy,[L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] … and [regadenson].

    Mixtures: Bandha You and Face Serum, Bandha You and Face MoistureCategories: Nucleic Acids, Nucleotides, and Nucleosides
  10. Drug

    Chlordiazepoxide

    go.drugbank.com/drugs/DB00475
    ApprovedIllicit

    An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.

    Mixtures: Corium Cap, CLIXIDCategories: Hypnotics and Sedatives, Benzodiazepines and benzodiazepine derivatives