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Octenidine
go.drugbank.com/drugs/DB12624InvestigationalOctenidine is under investigation in clinical trial NCT02697162 (Antiseptic-coated Intermittent Urinary Catheter).
Mixtures: Linola sept 1 mg/g + 20 mg/g Wund-Spray zur Anwendung auf der Haut, Lösung, Linola sept 1 mg/g + 10 mg/g Wund-GelCategories: Heterocyclic Compounds, 1-RingTrospium
go.drugbank.com/drugs/DB00209ApprovedInvestigationalTrospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that causes the bladder muscles to contract uncontrollably. … [L6208] An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes, loss of control over urination.
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: Mar-trospium, Trospium Chloride ERRescinnamine
go.drugbank.com/drugs/DB01180ApprovedRescinnamine is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug. It is an alkaloid obtained from _Rauwolfia serpentina_ and other species of _Rauwolfia_.
Synonyms: Trimethoxy cinnamoyl reserpate de methylInternational brands: Tsuruselpi SPentoxifylline
go.drugbank.com/drugs/DB00806ApprovedInvestigationalPentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties. … A branded product, PENTOXIL, marketed by Upsher-Smith Laboratories, and generic forms marketed by Valeant Pharmaceuticals and APOTEX have been available since the late 1990s.[L30300]
Mixtures: Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5%Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingEstriol
go.drugbank.com/drugs/DB04573ApprovedInvestigationalVet approvedA hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen.
International brands: Synapause EMixtures: GYNOFLOR 50 MG/0.03 MG VAJİNAL TABLET, 6 ADETBenzethonium
go.drugbank.com/drugs/DB11125ApprovedThere is evidence that benzethonium acts as a spermatocide but may cause vaginal irritation [A32304]. … Benzethonium was identified as a novel cancer-specific compound by cell-based small-molecule screen [A32298].
Mixtures: Terrasil Wound Care MAX, Terrasil Skin Repair MAXProducts: Ino-F-san Instant Hand Sanitizer, Handi-SanRocuronium
go.drugbank.com/drugs/DB00728ApprovedInvestigationalIt is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery … [Sugammadex] is a γ-cyclodextrin derivative that has been introduced as a novel agent to reverse the action of rocuronium.
Products: BROMURO DE ROCURONIO 50 MG/5 ML SOLUCION INYECTABLE, BROMURO DE ROCURONIO 50 MG / 5 ML SOLUCIÓN INYECTABLESaxagliptin
go.drugbank.com/drugs/DB06335ApprovedInvestigationalSaxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Mixtures: KOMBIGLYZE ® XR 5 MG/ 1000 MG, Kombiglyze XR Tablet 5/500mgCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesVindesine
go.drugbank.com/drugs/DB00309ApprovedInvestigationalWithdrawnVinblastine derivative with antineoplastic activity against cancer. Major side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (antineoplastic combined chemotherapy protocols).
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: 3-carbamoyl-4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine, 3-(aminocarbonyl)-O4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastineHaloperidol
go.drugbank.com/drugs/DB00502ApprovedInvestigationalIn addition, they block many receptors other than the primary target (dopamine receptors), such as cholinergic or histaminergic receptors, resulting in a higher incidence of side effects such as sedation … Inter-ethnic and pharmacogenetic differences in haloperidol metabolism may possibly explain these observations.
Synonyms: 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-oneInternational brands: Einalon S