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Selumetinib
go.drugbank.com/drugs/DB11689ApprovedInvestigational[A193608] It is a genetic, autosomal dominant condition resulting from mutations of the NF1 gene, which can lead to various complications, including the development of multiple tumours in the nervous system … [A193533,A193608] While some patients with this disorder develop PNs, this is considered relatively uncommon compared to other variants of NF-1.
Products: KOSELUGO HARD CAPSULES 10MG, KOSELUGO HARD CAPSULES 25MGPrucalopride
go.drugbank.com/drugs/DB06480ApprovedInvestigational[A37348] The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. … Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties.
Products: RESOLOR 1mg Film Coated Tablets, RESOLOR 1MG FILM KAPLI TABLET, TABLET, 14 ADETTobramycin
go.drugbank.com/drugs/DB00684ApprovedInvestigational[L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and ototoxicity, yet it remains a valuable option in the face of growing resistance to front-line antibiotics … such as β-lactams and cephalosporins.
Mixtures: DEXAVITAL TOBRAMICIDADEXAMETASONA(3 MG+1MG)/ML, TOBRAMICINA E DESAMETASONE EGProducts: Nebcin Inj 10mg/ml, Nebcin Inj 10mg/ml (vantage Vial)Travoprost
go.drugbank.com/drugs/DB00287ApprovedInvestigationalIt is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. … [L49434] Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity at the prostanoid receptor, reporting a higher efficacy in reducing intraocular pressure and a reduced
Mixtures: TRAVO/TIMOL AL 40UG/ML+5MG, TRAVO/TIMOL AL 40UG/ML+5MGProducts: PMS-travoprost Z, TRAVOPROST PH&T EYE DROPS SOLUTION 40MCG/MLZonisamide
go.drugbank.com/drugs/DB00909ApprovedInvestigationalIn 1989, it was approved for commercial use in Japan. The US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] … Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.
Products: ZONISOL 20MG/ML SUE, ZONEGRAN 25MGTrandolapril
go.drugbank.com/drugs/DB00519ApprovedInvestigationalIt is metabolized to its biologically active diacid form, trandolaprilat, in the liver. … Trandolapril may be used to treat mild to moderate hypertension, to improve survival following myocardial infarction in clinically stable patients with left ventricular dysfunction, as an adjunct treatment
Mixtures: TARKA 180MG/2MG, TARKA 180MG/2MGProducts: UDRIK 1MG, UDRIK 2MGNitroglycerin
go.drugbank.com/drugs/DB00727ApprovedInvestigational[L42445] It is also used to induce intraoperative hypotension.[L7099] … Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent [L38369] that was first discovered in 1847.
Mixtures: NITROGLICERINA 0.1 MG/ML EN DEXTROSA 5% SOLUCION INYECTABLEProducts: NITRODERM TTS 10 (10MG/24HR), NITROGLICERINA EN DEXTROSA AL 5% 50MG/250MLBrompheniramine
go.drugbank.com/drugs/DB00835ApprovedHistamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Mixtures: Bio T Pres-B, Good Neighbor Pharmacy Cold and CoughProducts: Dimegan Inj 10mg/ml, Dimetane Elixir 2mg/5mlAtenolol
go.drugbank.com/drugs/DB00335ApprovedInvestigationalAtenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and received FDA approval in September, 1981.
Mixtures: ATENOCOMP 1A 100MG/25MG, ATENOCOMP 1A 100MG/25MGProducts: CORATEN PA, JUVENTAL 25MGBismuth subgallate
go.drugbank.com/drugs/DB13909Approvedinternal deodorant where it is often employed as the primary active ingredient. … Possessing protective effects on the gastric mucosa, strong astringent effects, and not as yet elucidated antimicrobial and hemostatic actions, bismuth subgallate is most commonly available as an over-the-counter
Products: Stomax - Tab 400mg, Devrom Chew Tab 200mg