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Ropinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalIn 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547]. … It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease.
Products: ROPINIROLO EG, ROPINIROLO EG STADAKetorolac
go.drugbank.com/drugs/DB00465ApprovedInvestigationalKetorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. … [L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511]
Mixtures: ONEMER DTProducts: KETOROLAC EG, ASANDOL 30MG/12MLBisacodyl
go.drugbank.com/drugs/DB09020ApprovedInvestigational[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300]
Mixtures: BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADETProducts: Soflax EX 5, Soflax EX 10Guaifenesin
go.drugbank.com/drugs/DB00874ApprovedInvestigationalVet approvedAlthough it is principally believed that guaifenesin elicits an action to facilitate productive cough to manage chest congestion [A177661, L6100, F4516, F4522, F4525], it is not known whether the agent … used as an expectorant [F4525].
Mixtures: Acetaminophen 500mg, Dextromethorphan HBr 10mg, Guaifenesin 200mg, Phenylephrine HCl 5mg, BRELAX 1,5 MG+66,5 MG/5 ML ŞURUP, 100 MLProducts: ROBITUSSIN EX SYRUP 200 mg/10 ml, Mucus ERDextromethorphan
go.drugbank.com/drugs/DB00514ApprovedInvestigational[A215412] Although similar in structure to other opioids, it has minimal interaction with opioid receptors.[A215412] Dextromethorphan was granted FDA approval before 3 December 1957.
Mixtures: BENICAL 10 MG+20MG+2MG/5 ML SURUP, 100 ML, COUGH - EN PLUSCategories: Uncompetitive N-methyl-D-aspartate Receptor AntagonistPhenolphthalein
go.drugbank.com/drugs/DB04824ApprovedWithdrawnPhenolphthalein was withdrawn in Canada due to concerns with carcinogenicity in 1997.
Mixtures: EX-lax Light Formula Lax W Stool Soften TabCategories: Compounds used in a research, industrial, or household settingTapentadol
go.drugbank.com/drugs/DB06204ApprovedInvestigationalIt is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. … The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011.
Products: Nucynta ER Tablets 50 mg, Nucynta ER Tablets 100 mgPramipexole
go.drugbank.com/drugs/DB00413ApprovedInvestigationalIt was first approved by the FDA in 1997 [L5882]. … It is a _non-ergot dopamine agonist_ drug that is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement) [A176867].
Synonyms: (S)-N 6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamineInternational brands: Sifrol ERPomalidomide
go.drugbank.com/drugs/DB08910ApprovedInvestigationalPomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.
Products: POMALYST® 3MG, POMALYST CAPSULE 3MGPindolol
go.drugbank.com/drugs/DB00960ApprovedInvestigational[L32353] Early research into the use of pindolol found it had chronotropic effects, and so further investigation focused on the treatment of arrhythmia. … [A231059] Research into pindolol's use in the treatment of hypertension began in the early 1970s.[A231064] Pindolol was granted FDA approval on 3 September 1982.[L32348]
Products: Gen-pindolol Tab 15mg, VISKEN 5MG