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Prednisone
go.drugbank.com/drugs/DB00635ApprovedInvestigationalVet approvedA synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. Prednisone was granted FDA approval on 21 February 1955.
Categories: Corticosteroid Hormone Receptor Agonists, P-glycoprotein inducersProducts: Prednisone D/P, P- Pack Prednisone 20mg, 7- Day Tapering Dose PackClofibrate
go.drugbank.com/drugs/DB00636ApprovedWithdrawnA fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
Synonyms: Ethyl 2-(p-chlorophenoxy)isobutyrate, alpha-p-Chlorophenoxyisobutyryl ethyl esterCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersPentazocine
go.drugbank.com/drugs/DB00652ApprovedVet approvedIt is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
International brands: Talwin PXCategories: P-glycoprotein substratesMagnesium sulfate
go.drugbank.com/drugs/DB00653ApprovedInvestigationalVet approvedA small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and...
Products: Pepsom Flying P Epsom SaltTrazodone
go.drugbank.com/drugs/DB00656ApprovedInvestigationalTrazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. … used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor
Categories: P-glycoprotein inducers, Cytochrome P-450 SubstratesFlumethasone
go.drugbank.com/drugs/DB00663ApprovedVet approvedFlumethasone is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. As it is a privalate salt, its anti-inflammatory action is concentrated at the site of applicati...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEpinephrine
go.drugbank.com/drugs/DB00668ApprovedInvestigationalVet approvedEpinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersen...
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsWarfarin
go.drugbank.com/drugs/DB00682ApprovedInvestigationalWarfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesMidazolam
go.drugbank.com/drugs/DB00683ApprovedIllicitInvestigationalMidazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in th...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesFlurazepam
go.drugbank.com/drugs/DB00690ApprovedIllicitA benzodiazepine derivative used mainly as a hypnotic.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates