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Colistin
go.drugbank.com/drugs/DB00803ApprovedInvestigationalIt is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes.
Tafenoquine
go.drugbank.com/drugs/DB06608ApprovedInvestigational[A35690] Tafenoquine was further developed collaboratively between GlaxoSmithKline and Medicines for Malaria Venture.[A35677] It was FDA approved on July 20, 2018.[L3770] … [A35671, A35690] It was discovered by the scientists at the Walter Reed Army Institute of Research in 1978 as a substitute for primaquine that would be more effective against relapsing vivax malaria.
Safrazine
go.drugbank.com/drugs/DB09253ApprovedWithdrawnIn 1960, it was used as an antidepressant but it is now discontinued.
Prednisolone phosphate
go.drugbank.com/drugs/DB14631ApprovedInvestigationalVet approved[A187463] Prednisolone phosphate was granted FDA Approval on 19 December 1973.[L14144]
Cytochrome c oxidase subunit 2
go.drugbank.com/bio_entities/BE0003900TargetThermus thermophilusSubunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
Synonyms: Cytochrome c ba(3) subunit IIProcaine benzylpenicillin
go.drugbank.com/drugs/DB09320ApprovedVet approvedProcaine benzylpenicillin (INN), also known as procaine G penicillin, is an injectable antiobiotic.
Dehydrocholic acid
go.drugbank.com/drugs/DB11622ApprovedDehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with chromic acid [A33022]. It has been used for stimulation of biliary lipid secretion. … The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada.
Products: Dycholium Tablet 300mgArformoterol
go.drugbank.com/drugs/DB01274ApprovedThe use of arformoterol is pending revision due to safety concerns in regards to an increased risk of severe exacerbation of asthma symptoms, leading to hospitalization as well as death in some patients
Metixene
go.drugbank.com/drugs/DB00340ApprovedMetixene (or methixene) is a anticholinergic used as an antiparkinsonian agent.
Zenocutuzumab
go.drugbank.com/drugs/DB15559ApprovedInvestigational[L56179] This approval was expedited following receipt of an FDA Commissioner’s National Priority Voucher. … [L51983] In May 2026, zenocutuzumab was granted additional approval by the US FDA for use in NRG1-positive cholangiocarcinoma.