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Displaying results 2321 - 2330 of 10000 in total
  1. Drug

    Procaine benzylpenicillin

    go.drugbank.com/drugs/DB09320
    ApprovedVet approved

    Procaine benzylpenicillin (INN), also known as procaine G penicillin, is an injectable antiobiotic. … It is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and the local anaesthetic agent procaine in equimolar amounts.

    Synonyms: Penicillin G procaineMixtures: PROKAIN PENICILLIN 3.1.400.000 IU IM ENJEKSİYONLUK TOZ, 10 ADET, PROKAIN PENICILLIN 3.1.800.000 IU IM ENJEKSİYONLUK TOZ, 10 ADET
  2. Drug

    Proguanil

    go.drugbank.com/drugs/DB01131
    Approved

    Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, _Plasmodium falciparum_ and _Plasmodium vivax_, from reproducing once it is in the red blood cells.

    Mixtures: Malarone 250 mg/100 mg Filmtabletten, MALARONE (250/100 MG TABLETS)Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates
  3. Drug

    Sargramostim

    go.drugbank.com/drugs/DB00020
    ApprovedInvestigational

    Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. … Substitution of Leu23 leads to a difference from native protein.

  4. Drug

    Inositol nicotinate

    go.drugbank.com/drugs/DB08949
    ApprovedWithdrawn

    It is used in food supplements as a source of niacin (vitamin B3), where hydrolysis of 1 g (1.23 mmol) inositol hexanicotinate yields 0.91 g nicotinic acid and 0.22 g inositol. … Inositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and vasodilator.

    Mixtures: Inositol Nicotinate 250 mg, Inositol Nicotinate 250 mg
  5. Drug

    Atovaquone

    go.drugbank.com/drugs/DB01117
    ApprovedInvestigational

    Atovaquone is a hydroxynaphthoquinone, or an analog of ubiquinone, that has antimicrobial and antipneumocystis activity. It is being used in antimalarial protocols.

    Mixtures: Malarone 250 mg/100 mg Filmtabletten, MALARONE (250/100 MG TABLETS)Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Inhibitors
  6. Drug

    Setmelanotide

    go.drugbank.com/drugs/DB11700
    ApprovedInvestigational

    [A224449] Patients taking setmelanotide experienced an average weight loss of 0.6 kg/week. … [A224449] Earlier attempts at agonizing MC4R (such as LY2112688) lead to successful weight loss, but also an increase in blood pressure and heart rate.

  7. Drug

    Bisoctrizole

    go.drugbank.com/drugs/DB11262
    Approved

    10% [F90]. … Bisoctrizole, or methylene bis-benzotriazolyl tetramethylbutylphenol, is a broad-spectrum organic UV filter that is marketed as Tinosorb M [A19212].

    Mixtures: SPF 50, Emulsion SPF 50+
  8. Drug

    Piperaquine

    go.drugbank.com/drugs/DB13941
    ApprovedInvestigational

    Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China [A31550]. … Its use declined in the 1980's as piperaquine resistant strains of *Plasmodium falciparum* appeared and artemisinin derivatives became available.

    Mixtures: EURARTESIM 320 MG/40 MG FILM COATED TABLETS, D-ARTEPPCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Inhibitors
  9. Drug

    Tegafur

    go.drugbank.com/drugs/DB09256
    ApprovedInvestigational

    ensuring high concentrations of 5-FU at a lower dose of tegafur [L933]. … Tegafur (INN, BAN, USAN) is a prodrug of [DB00544] (5-FU), an antineoplastic agent used as the treatment of various cancers such as advanced gastric and colorectal cancers.

    International brands: Ai Yi, ESUEEW AN TCategories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index
  10. Drug

    Calcium glycerophosphate

    go.drugbank.com/drugs/DB11264
    Approved

    The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. … It is also present in dental or oral hygiene products due to its cariostatic effects.

    Mixtures: Alsimine W Vitamins A D