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Displaying results 2321 - 2330 of 10000 in total
  1. Drug

    Sargramostim

    go.drugbank.com/drugs/DB00020
    ApprovedInvestigational

    Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues.

  2. Drug

    Ibudilast

    go.drugbank.com/drugs/DB05266
    Investigational

    Ibudilast is an anti-inflammatory and neuroprotective oral agent which shows an excellent safety profile at 60 mg/day and provides significantly prolonged time-to-first relapse and attenuated brain volume … (codes: AV-411 or MN-166), but is approved for use as an antiinflammatory in Japan.

    Categories: Phosphodiesterase 5 InhibitorsInternational brands: Ke Tas
  3. Drug

    Lactobacillus plantarum

    go.drugbank.com/drugs/DB11360
    Investigational

    *L. plantarum* produces different antimicrobial agents such as organic acids, hydrogen peroxide, diacetyl, bacteriocins, and antimicrobial peptides [A27208]. … *Lactobacillus plantarum* is a member of Lactobacillus, or lactic acid bacteria, that it is widely used in the food industry as a microbial starter and probiotic microorganism.

    Mixtures: BİOBER-ZN ORAL SÜSPANSİYON İÇEREN FLAKON, 5 ADETProducts: Kimchi Lactic Acid 1000, Kimchi Lactobacillus 1000
  4. Drug

    Oxybenzone

    go.drugbank.com/drugs/DB01428
    Approved

    It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.

    Mixtures: Olay Professional ProX Age Repair SPF 30, Olay Professional ProX Age Repair Broad Spectrum SPF 30Synonyms: 2-Benzoyl-5-methoxyphenol
  5. Drug

    UCB7362

    go.drugbank.com/drugs/DB17096
    Experimental

    It has shown high potency in biochemical (IC<sub>50</sub> = 7 nM), _in vitro_ (_P. falciparum_ 3D7 lactate dehydrogenase growth inhibition assay IC<sub>50</sub> = 10 nM), and _in vivo_ (50 mg/kg dose

  6. Drug

    Sacubitril

    go.drugbank.com/drugs/DB09292
    ApprovedInvestigational

    It was approved by the FDA after being given the status of priority review for on July 7, 2015. … Under normal conditions, neprilysin breaks down other vasodilating peptides and also vasoconstrictors such as angiotensin I and II, endothelin-1 and peptide amyloid beta-protein.

    Mixtures: ONEPTUS 97 MG/103 MG FILM KAPLI TABLET, 56 ADET, ENTRESTO 50 MG
  7. Drug

    Dipotassium phosphate

    go.drugbank.com/drugs/DB09414
    ApprovedInvestigational

    Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.

    Mixtures: ISOLYTE-M %5 DEKSTROZ PVC 1000 ML(SETLI), ISOLYTE-M %5 DEKSTROZ PVC 1000 ML(SETSIZ)
  8. Drug

    Vorasidenib

    go.drugbank.com/drugs/DB17097
    ApprovedInvestigational

    [A264209] It works by suppressing the levels of D-2-hydroxyglutarate (2-HG), an oncometabolite produced by mutant IDH1 and IDH2 isoforms. … [L51139] Vorasidenib displayed improved brain penetration and higher drug exposure compared to other IDH inhibitors such as [ivosidenib] and [enasidenib].

    Synonyms: 1,3,5-triazine-2,4-diamine, 6-(6-chloro-2-pyridinyl)-n2,n4-bis((1r)-2,2,2-trifluoro-1-methylethyl)-Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 Substrates
  9. Drug

    Afamelanotide

    go.drugbank.com/drugs/DB04931
    Approved

    [L9092] Despite its relatively recent approval, afamelanotide has been available for use as an orphan drug in both the US and EU since 2008.[L9122,L9125]

    Synonyms: MT-I
  10. Drug

    Centella asiatica

    go.drugbank.com/drugs/DB14256
    Approved

    Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Ma Ti Cao WholeProducts: StemCell TeN 10 Revolutionary skin theraphy, Madepair %1 Merhem, 40 g