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Piperonyl butoxide
go.drugbank.com/drugs/DB09350ApprovedVet approvedIt has no pesticidal activity of its own, but acts to increase the activity of pesticides such as carbamates, pyrethrins, pyrethroids, and rotenone. … Piperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is used for the treatment of head, pubic (crab), and body lice. Piperonyl butoxide is a synergist.
Mixtures: Up and up lice killing maximum strength, Medi and Lice Lice KillingNaldemedine
go.drugbank.com/drugs/DB11691ApprovedInvestigationalNaldemedine was approved in 2017 in both the US and Japan for the treatment of Opioid-induced Constipation. … It is a modified form of [DB00704] to which a side chain has been added to increase molecular weight and polar surface area resulting in restricted transport across the blood brain barrier.
Categories: Alimentary Tract and MetabolismTrifarotene
go.drugbank.com/drugs/DB12808ApprovedInvestigationalas compared to older, less selective retinoids. … to vitamin A and are analogous only in function.
Categories: Skin and Mucous Membrane AgentsNasal Polyps
go.drugbank.com/conditions/DBCOND0004147Drugs: BudesonideSynonyms: Multiple polyps of nasal cavity and/or nasal sinus, Multiple polyps of nasal cavity and/or nasal sinus (disorder)Levacetylmethadol
go.drugbank.com/drugs/DB01227ApprovedWithdrawnLevacetylmethadol was withdrawn from use in the European Union due to its high risk of QT interval prolongation. The production of levacetylmethadol in the US has ceased as well.[L44052,T862] … Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence.
Donislecel
go.drugbank.com/drugs/DB17961Approved[L47196] Donislecel was approved by the FDA on June 28, 2023, and is available under the brand name LANTIDRA from CellTrans Inc.[L47196] … , by not relying on exogenous and intentional insulin administration to control blood glucose.
Categories: Cellular and Gene Therapy, Alimentary Tract and MetabolismCysteamine
go.drugbank.com/drugs/DB00847ApprovedInvestigational[A218721] Several preparations of cysteamine exist for the treatment of cystinosis manifestations, some in capsule form, and others in ophthalmic solution form. … [L15606] Cysteamine eye drops are a practical and effective option for those affected by ocular cystinosis.
Categories: Amino Acids and Derivatives, Alimentary Tract and MetabolismLoncastuximab tesirine
go.drugbank.com/drugs/DB16222ApprovedInvestigational[L45206] This therapy was developed by ADC Therapeutics and its accelerated approval for relapsed or refractory B-cell lymphoma is based on promising results from the LOTIS-2 clinical trial. … [A234439] Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsFenproporex
go.drugbank.com/drugs/DB01550ApprovedIllicitWithdrawnIn 2006 and 2009, the FDA issued warnings that it had been detected in diet pills sold online, and imported from foreign manufacturers. … It is listed as an illicit substance in many countries due to addiction issues and listed as a prohibited substance by the World Anti-Doping Agency.
Povidone
go.drugbank.com/drugs/DB11061ApprovedInvestigationalWithdrawnPovidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant … It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier.
Mixtures: Rohto Sun and Sport, Redness reliever and Lubricant