Nasal Polyps (DBCOND0004147)

Identifiers

Synonyms
Polyp of Nasal Sinus / Polyp, Nasal / Polyps, Nasal / Nasal Polyp / Nasal Polyposis / Nasal polyps / Nasal polyp, unspecified / Polyp of nasal cavity / Polyp of nasal cavity (disorder) / Unspecified nasal polyp / Polyps nasal / Other polyp of sinus / Sinus polyp / Polyp of nasal sinus (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Budesonide
A corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02569437
Doxycycline in Treating Patients With Chronic Rhinosinusitis With Nasal Polypstreatment2terminated
NCT03454607
Foot Controlled Robotic Endoscope Enabled Robot FESSNo drug interventionsotherNot Availableterminated
NCT05923047
Mepolizumab and In-office Nasal Polypectomy in Patients With Chronic Rhinosinusitis (CRS). A Three Arm Study.treatment4not_yet_recruiting
NCT05474924
The Role of Budesonide Intrapolyp Injection in CRSwNPtreatment4unknown_status
NCT03704415
Aggravated Airway Inflammation: Research on Genomics and Optimal Operative Treatment (AirGOs Operative)No drug interventionstreatmentNot Availableactive_not_recruiting
NCT05287841
Does Batten Grafting Improve Nasal Outcomes in Septoplasty and Turbinate Reduction?No drug interventionstreatmentNot Availablerecruiting
NCT03102190
Trial of Topical Verapamil in Chronic Rhinosinusitis With Nasal Polypstreatment1terminated
NCT03943121
The Effects of Steroid-eluting Stent Implant for the Treatment of Eosinophilic Chronic Rhinosinusitis With Nasal PolypsNo drug interventionstreatmentNot Availableunknown_status
NCT00739921
The Polymerase Chain Reaction (PCR) Analysis of Nasal Polyps for Fungal DNANo drug interventionsdiagnosticNot Availablecompleted
NCT00465543
Mint Tea for the Treatment of Nasal PolypsNo drug interventionstreatment2completed
NCT00215787
Investigation of the Association Between Nasal Polyposis and Extraesophageal Reflux DiseasetreatmentNot Availablecompleted
NCT01819454
The Diagnostics of Extraesophageal Reflux With the Restech SystemNo drug interventionsdiagnosticNot Availablecompleted
NCT00835445
Biopsies and PolypsNo drug interventionsNot AvailableNot Availablecompleted
NCT04805398
Subcutaneously CM310/Placebo in Patients With Chronic Rhinosinusitis With Nasal Polyposis (CROWNS-1)treatment2completed
NCT03085797
Effect of Mepolizumab in Severe Bilateral Nasal Polypstreatment3completed
NCT06070311
Wound Healing After Endoscopic Sinus SurgerytreatmentNot Availablenot_yet_recruiting
NCT03681093
Study of Efficacy of Fevipiprant in Patients With Nasal Polyposis and Asthmatreatment3completed
NCT01920893
An Evaluation of Dupilumab in Patients With Nasal Polyposis And Chronic Symptoms Of Sinusitistreatment2completed
NCT01222871
Treatment of Early Nasal Polyposis With Topical Triamcinolonetreatment1 / 2terminated
NCT05405478
Omalizumab Efficacy in Patients With Refractory Nasal Polypstreatment4unknown_status
NCT00378378
Study of Nasonex® for the Treatment of Nasal Polyps in Pediatric Subjects Between Ages of 6 and Less Than 18 Years Old (P04292)treatment3completed
NCT04804488
Retrospective Study for Recurrent Nasal PolyposisNo drug interventionsNot AvailableNot Availablecompleted
NCT00731185
Mometasone Furoate Nasal Spray for Treatment of Nasal Polyposis After Surgery (Study P03218)treatment3completed
NCT03362515
Treatment of Post-Operative Sinonasal Polyposis With Topical Furosemidetreatment2terminated
NCT03280537
A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitus With Nasal Polypstreatment3completed
NCT02024659
Effects and Safety of Budesonide Inhalation Suspension Via Transnasal Nebulization in Nasal Polypstreatment2 / 3completed
NCT05094570
Interleukin-4Ra Blockade by Dupilumab Decreases Staphylococcus Colonization and Increases Microbial Diversity in CRSwNPtreatment4recruiting
NCT05828199
The Effect of Intraoperative Infusion of Dexmedetomidine Versus Low Dose Ketaminetreatment1recruiting
NCT01564849
The Clinical Efficacy of Topical Nasal Pomegranate Fruit Extract for Patients With Chronic RhinosinusitisNo drug interventionsNot AvailableNot Availableunknown_status
NCT06461949
Study of Dupilumab 300 mg Every Other Week After Endoscopic Sinus Surgery in Patients With Allergic Fungal Rhinosinusitis (AFRS) on a Background Therapy With Intranasal Corticosteroid Spraytreatment3withdrawn
NCT01732536
Steroid-Releasing S8 Sinus Implant for Recurrent Nasal Polypstreatment2 / 3completed
NCT00440219
The Effect of Preoperative Oral Prednisone on the Operative Field During Nasal Polypectomy.treatment3completed
NCT03374124
The Surgical Prognosis Based Diagnostic Strategy for Eosinophilic Chronic RhinosinusitisNo drug interventionsNot AvailableNot Availableunknown_status
NCT05009758
Moving Towards Precision Medicine in United Airways Disease: Unraveling Inflammatory Patterns in Asthmatic Patients With or Without Nasal PolypsNo drug interventionsscreeningNot Availablerecruiting
NCT03326063
Therapeutic Control of Aspirin-Exacerbated Respiratory Disease With Ifetrobantreatment2completed
NCT00788463
A Comparison of Beclomethasone Aqueous Spray and Aerosol Delivery Systems in Nasal Polypstreatment2completed
NCT05672030
Role of IL-5R Signaling in Non-eosinophil Upper Airway Cells in CRSwNPNo drug interventionsNot AvailableNot Availablerecruiting
NCT03478930
An Extension Study of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polypstreatment3completed
NCT03963648
NO Measurements in Screening for Asthma and OSA, in Patients With CRSwNPNo drug interventionsdiagnosticNot Availableunknown_status
NCT05180357
RANS. Study in Patients With Severe Eosinophilic Asthma and Nasal Polyps.No drug interventionsNot AvailableNot Availablecompleted
NCT01295866
Evaluation Effects of Nasal Nitric Oxide Measurements Are Associated With Atopy Status in Chronic Nasal InflammationNo drug interventionsNot AvailableNot Availablecompleted
NCT04261582
Genetics and Genomics of Aspirin Exacerbated Respiratory Disease (AERD)No drug interventionsNot AvailableNot Availablesuspended
NCT06036927
A Clinical Study of TQC2731 Injection in the Treatment of Chronic Rhinosinusitis With Nasal PolypsNo drug interventionstreatment2recruiting
NCT04104594
Olfaction and Inflammation in Chronic Rhinosinusitis With Nasal PolypsNo drug interventionsotherNot Availableterminated
NCT02194062
Comparison of Nasal Steroids After FESS in CRSwNPtreatmentNot Availablecompleted
NCT01362244
Mepolizumab in Nasal Polyposistreatment2completed
NCT03965767
Does The Combined Use Of Local And Intravenous Tranexamic Acid Offer Better Surgical Field Quality During Functional Endoscopic Sinus Surgery? A Placebo-Controlled Clinical Trialtreatment3unknown_status
NCT02071667
Association of Periostin Levels and Chronic SinusitisNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01198912
Influence of Oral Doxycycline on Wound Healing After Endonasal Endoscopic Sinus Surgery for Chronic Rhinosinusitis With and Without Nasal Polyposis: a Double-blind Randomized Placebo-controlled Trialtreatment2completed
NCT04185012
NAsal Polyps: Inflammatory & Molecular Phenotyping of Responders to Benralizumabtreatment3unknown_status
NCT04888910
Novel Inflammatory Markers in Different Phenotypes of Severe AsthmaNo drug interventionsNot AvailableNot Availableunknown_status
NCT02975310
In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal PolypsNo drug interventionstreatmentNot Availablerecruiting
NCT03280550
A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polypstreatment3completed
NCT05274750
Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polypstreatment3active_not_recruiting
NCT01827423
Squamous Cell Carcinoma Antigen Analysis at the University Hospital OstravaNo drug interventionsdiagnosticNot Availablecompleted
NCT02454608
Trial of Verapamil in Chronic RhinosinusitistreatmentNot Availableterminated
NCT02427503
ATP Project (Asthma afTer Polypectomy)No drug interventionsNot AvailableNot Availablecompleted
NCT00841802
Chronic Rhinosinusitis With or Without Nasal Polyps Steroid Studytreatment4withdrawn
NCT03427502
Anterior Ethmoidal Nerve Block in Prevention of Postoperative AgitationpreventionNot Availablecompleted
NCT02110654
Comparison of Daily Mometasone Furoate Nasal Spray Alone Versus a Combination With Montelukast for Treatment of Chronic Rhinosinusitis With Asthma After Functional Endoscopic Sinus Surgerytreatment4completed
NCT03151954
The Activation of Hippo Pathway in Nasal PolypsNo drug interventionstreatmentNot Availableunknown_status
NCT03694847
Asthma With Nasal PolyposisNo drug interventionsNot AvailableNot Availablecompleted
NCT04607005
Efficacy and Safety of Mepolizumab in Adults With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)/ Eosinophilic Chronic Rhinosinusitis (ECRS)treatment3completed
NCT03450083
Benralizumab Effect on Severe Chronic Rhinosinusitis With Eosinophilic Polyposistreatment2completed
NCT04105361
Impact of Posterior Nasal Neurectomy With Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis With Nasal Polyposis:A Comparative StudyNo drug interventionspreventionNot Availableunknown_status
NCT05869071
Assessment of Oral and Nasal Breathing With Sensors Analyzing AlgorithmNo drug interventionsNot AvailableNot Availablerecruiting
NCT06501807
BIOlogics in Severe Nasal POlyposis SurvEy.: a French RegistrytreatmentNot Availablenot_yet_recruiting
NCT05575037
Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Diseasetreatment2recruiting
NCT02484859
Comparison of Metoprolol and Tramadol With Remifentanil in Endoscopic Sinus Surgeryother4completed
NCT03607175
Adjunctive Treatment for Chronic Rhinosinusitis With Nasal Polyposistreatment2 / 3not_yet_recruiting
NCT02533206
Pilot Study of The EPIC TrialNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00788749
Medical Polypectomy and Predictors of Responsetreatment4completed
NCT05865496
A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal PolypsNo drug interventionstreatment2active_not_recruiting
NCT06362122
Anatomo-clinico-biological Profiles in Severe Nasal PolypsNo drug interventionsbasic_scienceNot Availablerecruiting
NCT01386125
A Study of the Effectiveness and Safety of Mometasone Furoate Nasal Spray (MFNS, SCH 032088) for the Treatment of Nasal Polyps (P05604)treatment3completed
NCT03369574
Study of Chronic Rhinosinusitis Symptoms in Asthma Patients Undergoing Treatment With ReslizumabNot AvailableNot Availablewithdrawn
NCT06182982
Auriculotherapy for Intraoperative Blood Pressure ControlNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02855931
Study to Compare Resection Versus Preservation of the Middle Turbinate in Surgery for Nasal PolypsNo drug interventionstreatmentNot Availablecompleted
NCT04996576
Infrazygomatic Versus Intranasal Injection Sphinopalatine Ganglion Blockade Effect on Surgical Field in FESSNo drug interventionsotherNot Availablecompleted
NCT01616160
An Open-label Study to Identify Molecular Markers of Steroid Resistancebasic_science4terminated
NCT04852562
The Effect of Modified Radical Endoscopic Sinus Surgery on Eosinopilic Chronic Rhinosinusitus With Nasal PolypsNo drug interventionstreatmentNot Availablerecruiting
NCT02879929
Development and Validity of the DyNaChron Questionnaire for Chronic Nasal DysfunctionNo drug interventionsNot AvailableNot Availablecompleted
NCT02476929
Detection and Use of Nasal Nitrous Oxide and the Electronic NoseNo drug interventionsbasic_scienceNot Availablecompleted
NCT03221192
Qualitative Analysis of Subject Experience of Nasal PolypsNo drug interventionsNot AvailableNot Availablecompleted
NCT03472144
Gel-Sinuplasty for Chronic Rhinosinusitis With and Without Nasal Polyposissupportive_care3unknown_status
NCT02874144
Anti-Inflammatory Agent in Sinusitistreatment2completed
NCT04583501
Preclinical Studies of Omalizumab in Chronic Rhinosinusitis With Nasal Polyposisbasic_science0completed
NCT01066104
Subcutaneous Omalizumab for Treatment of Chronic Rhinosinusitis With Nasal Polyposistreatment2completed
NCT05157412
Role of Doxycycline in Chronic Rhinosinusitis With Nasal Polypstreatment3completed
NCT01623310
12-Month OL Intranasal Fluticasone Propionate BID Using OptiNose Devicetreatment3completed
NCT05063981
Treatment With Mepolizumab on Patients With Severe Refractory Eosinophilic Asthma With or Without CRSwNP.Not AvailableNot Availablerecruiting
NCT03228914
Comparing Blood Loss and Visualization After the Preoperative Use of Topical 0.05% Oxymetazoline Versus 1:1000 Epinephrine Prior to Endoscopic Sinus Surgerytreatment4completed
NCT05281523
Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps (ANCHOR-2)treatment3active_not_recruiting
NCT03627286
Effect of Benralizumab in Patients With Severe Nasal Polypstreatment3recruiting
NCT01278719
The Factors Associated With the Formation of Nasal polyp-a Case Control and Descriptive StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT01631773
A Comparison of microRNA Samples in Patients With Nasal Polyps and Aspirin Exacerbated Respiratory Disease and Those With Nasal Polyps OnlyNo drug interventionsNot AvailableNot Availablecompleted
NCT00480298
Double-Blind Randomized Placebo-Controlled Trial on Clinical and Biological Effects of Oral Corticosteroids or Doxycyclin in Patients With Nasal Polyposistreatment2completed
NCT02734849
Study to Evaluate Multiple Doses in Patients With Nasal PolyposisNo drug interventionstreatment2completed
NCT02291549
S8 Sinus Implant in Chronic Sinusitis Patients With Recurrent Nasal Polypstreatment3completed
NCT04532736
Comparison of Methylprednisolone or Methotrexate in the Maintenance Treatment of Nasal Polyposistreatment2completed
NCT05131958
Nasality Evolution in a Nasal Polyposis Context : Multiparametric Evaluation : Articulatory (Imaging), Aerodynamics, Acoustics and PerceptionNo drug interventionsNot AvailableNot Availableunknown_status
NCT04157335
Efficacy and Safety Study of Benralizumab in Patient With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps (ORCHID)treatment3active_not_recruiting
NCT03401229
Efficacy and Safety Study of Benralizumab for Patients With Severe Nasal Polyposistreatment3completed
NCT03591068
Efficacy & Safety of OPN-375 Adults With Bilateral Nasal Polyps Using Nasoendoscopic Videotreatment3completed
NCT05056714
Development of a Severity Assessment Score for Nasosinus Polyposis (PSI Score)No drug interventionsNot AvailableNot Availablerecruiting
NCT01906697
The Effect of RF Turbinoplasty in Polypoid Change of Middle TurbinatesNo drug interventionstreatment3unknown_status
NCT02562924
The Efficacy of MEDIHONEY® for Chronic Rhinosinusitis With Nasal Polyposis After Functional Endoscopic Sinus SurgerytreatmentNot Availablecompleted
NCT03979716
Smell Exploration in Patients With Nasal Polyposis : Study by Functional Magnetic Resonance ImagingNo drug interventionsotherNot Availableunknown_status
NCT02784262
Botulinum Toxin Type A Block of the Sphenopalatine Ganglion in Chronic Rhinosinusitis With Nasal Polyposistreatment2completed
NCT03358329
Safety Evaluation of Repeat Placement of the S8 Sinus Implant in Chronic Sinusitis Patients With Nasal Polyps (ENCORE)No drug interventionstreatment3completed
NCT01393340
Clinical and Biological Effects of Anti-IgE (Omalizumab) in Patients With Bilateral Nasal Polyposis and Asthmatreatment2completed