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Umifenovir
go.drugbank.com/drugs/DB13609InvestigationalUmifenovir is an indole-based, hydrophobic, dual-acting direct antiviral/host-targeting agent used for the treatment and prophylaxis of influenza and other respiratory infections. It has been in use in Russia for approximately 25 years a...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesMetahexamide
go.drugbank.com/drugs/DB13675InvestigationalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesDexchlorpheniramine
go.drugbank.com/drugs/DB13679InvestigationalIt disrupts histamine signaling by competing with histamine for cell receptor sites on effector cells.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsQuingestanol
go.drugbank.com/drugs/DB13685ExperimentalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesRufloxacin
go.drugbank.com/drugs/DB13772InvestigationalRufloxacin is a quinolone antibiotic.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsPenfluridol
go.drugbank.com/drugs/DB13791InvestigationalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEnasidenib
go.drugbank.com/drugs/DB13874ApprovedInvestigationalEnasidenib is an orally available treatment for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with specific mutations in the isocitrate dehydrogenase 2 (IDH2) gene, which is a recurrent mutation...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesTestosterone cypionate
go.drugbank.com/drugs/DB13943ApprovedInvestigationalTestosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester. Its benefit compared to other testosterone derivatives is the slow rate of release after injection and ...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesStanolone acetate
go.drugbank.com/drugs/DB13951ExperimentalStanolone acetate is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester that was never marketed.
Categories: P-glycoprotein substratesEstradiol acetate
go.drugbank.com/drugs/DB13952ApprovedVet approvedAs a pro-drug of estradiol, estradiol acetate therefore has the same downstream effects within the body through binding to the Estrogen Receptor (ER) including ERα and ERβ subtypes, which are located in … exist in a dynamic equilibrium of metabolic interconversions, estradiol is the principal intracellular human estrogen and is substantially more potent than its metabolites, estrone and estriol at the receptor
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A1 Substrates