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Apalutamide
go.drugbank.com/drugs/DB11901ApprovedInvestigationalApalutamide was approved in February 2018 by the FDA as Erleada for the treatment of patients with non-metastatic prostate cancer that is resistant to treatment with hormone therapy (castration-resistant … Approximately 10 to 20 % of prostate cancer cases are castration-resistant, and up to 16% of these patients show no evidence of cancer metastasis at the time of castration-resistant diagnosis [L1295].
Fluoride ion
go.drugbank.com/drugs/DB11257ApprovedInvestigationalFluoride ions are found in various minerals but are only present in trace amounts in water. … Its various salt forms and minerals play numerous roles as chemical reagents, industrial chemicals, and commercial products.
Mixtures: Tri-Vi-Flor, Poly-Vi-Flor with IronMeningococcal polysaccharide vaccine group W-135
go.drugbank.com/drugs/DB13887ApprovedInvestigationalMeningococcal group W-135 polysaccharide is group-specific polysaccharide antigens extracted and purified from *Neisseria meningitidis* serogroup W-135. … It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup W-135.
Mixtures: MENVEO POWDER & SOLUTION FOR SOLUTION FOR INJECTION, Menveo Powder and Solution for Solution for InjectionQuetiapine
go.drugbank.com/drugs/DB01224ApprovedInvestigationalIt is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [clozapine] and [olanzapine].[A2189] … Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder.
Categories: Antidepressive Agents Indicated for DepressionElagolix
go.drugbank.com/drugs/DB11979ApprovedInvestigationalMoreover, women who are affected by this condition can suffer for up to six to ten years and visit multiple physicians before receiving a proper diagnosis [A35868, A35869, F801]. … Subsequently, as Orilissa (elagolix) was approved by the FDA under priority review [F815], this expedited new approval gives healthcare professionals another valuable option for treating the potentially
Seractide acetate
go.drugbank.com/drugs/DB09334ApprovedSeractide acetate is the acetate salt of full length human corticotropin.
Biotin
go.drugbank.com/drugs/DB00121ApprovedInvestigationalNutraceuticalIt occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Mixtures: For-2, SOLUVIT N FOR INFUSIONProducts: Tk-naxIcaridin
go.drugbank.com/drugs/DB14074InvestigationalIcaridin is reported to be less irritating than [Diethyltoluamide], another common insect repellant, and products containing up to 20% of icaridin are considered safe for long-term use in adults [A39231 … Piperidines are structural components of [piperine], which is a plant extract from the genus _Piper _, or pepper.
Categories: Compounds used in a research, industrial, or household settingMethaqualone
go.drugbank.com/drugs/DB04833ApprovedIllicitWithdrawnThe sedative-hypnotic activity was first noted by Indian researchers in the 1950s and in 1962 methaqualone itself was patented in the US by Wallace and Tiernan. … Its use peaked in the early 1970s as a hypnotic, sedative, and muscle relaxant commonly used for insomnia.
Citrulline
go.drugbank.com/drugs/DB00155InvestigationalNutraceuticalIts name is derived from citrullus, the Latin word for watermelon, from which it was first isolated. … It is made from ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle. It is also produced from arginine as a by-product of the reaction catalyzed by NOS family.