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Olutasidenib
go.drugbank.com/drugs/DB16267ApprovedInvestigational[L44256,L44261] It is indicated for the treatment of relapsed or refractory acute myeloid leukemia (AML) in patients with a susceptible IDH1 mutation as determined by an FDA-approved test. … [L44256] IDH1 mutations are common in different types of cancer, such as gliomas, AML, intrahepatic cholangiocarcinoma, chondrosarcoma, and myelodysplastic syndromes (MDS), and they lead to an increase
Mirtazapine
go.drugbank.com/drugs/DB00370ApprovedInvestigational[A177946] This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder. … [A178144,L6160] In addition to its beneficial effects in depression, mirtazapine has been reported to be efficacious in the off-label management of various other conditions.
Categories: Antidepressive Agents Indicated for Depression, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Co MirtazapineHelminth Infection
go.drugbank.com/conditions/DBCOND0082009Synonyms: Infection due to Class Cestoda and/or Class Trematoda and/or Phylum NemataTrimethobenzamide
go.drugbank.com/drugs/DB00662ApprovedInvestigationalIn dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate. … Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ).
Categories: Antihistamines for Systemic UseSodium oxybate
go.drugbank.com/drugs/DB09072ApprovedInvestigational[A251430] Due to its physiological effects, sodium oxybate is associated with a risk for substance misuse and abuse. … Sodium oxybate has been misused to stimulate body growth and to induce euphoria, disinhibition, and sexual arousal as a "party drug" or "club drug."
Ammonia N-13
go.drugbank.com/drugs/DB09326ApprovedAmmonia N 13 Injection, USP is used for imaging of the myocardium under rest or pharmacologic stress conditions to evaluate myocardial perfusion in patients with suspected or existing coronary artery disease … Ammonia N 13 Injection, USP is a positron emitting radiopharmaceutical that is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging.
Sotorasib
go.drugbank.com/drugs/DB15569ApprovedInvestigational[A187547] The drug [MRTX849] is also currently being developed and has the same target. … [A187550] Mutant KRAS discovered in 1982 but was not considered a druggable target until the mid-2010s.[A235168] It is the first experimental KRAS inhibitor.
Cenegermin
go.drugbank.com/drugs/DB13926ApprovedInvestigationalCenegermin also received Orphan Drug designation, which provides incentives to assist and encourage the development of drugs for rare diseases. … The approval of cenegermin consequently provides a novel topical treatment that has the potential capacity to offer total corneal healing for many patients who may use the agent.
Linzagolix
go.drugbank.com/drugs/DB17083ApprovedInvestigational[A253667] Linzagolix was approved for use in the European Union in June 2022 for the management of symptoms caused by uterine fibroids.[L43627] … [A253642,A253647] It is similar to other GnRH receptor antagonists like [cetrorelix], [relugolix], and [elagolix].
Magnesium cation
go.drugbank.com/drugs/DB01378ApprovedInvestigationalNutraceuticalWithdrawnMilk of magnesia is primarily used to alleviate constipation, but can also be used to relieve indigestion and heartburn. … When taken internally by mouth as a laxative, the osmotic force of the magnesia suspension acts to draw fluids from the body and to retain those already within the lumen of the intestine, serving to distend
Mixtures: MAGVEL 365 MG GRANÜL İÇEREN SAŞE, 10 ADET, MAGVEL 365 MG GRANÜL İÇEREN SAŞE, 20 ADET