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Brexpiprazole
go.drugbank.com/drugs/DB09128ApprovedInvestigationalIt has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. … It also displays stronger antagonism at the 5-HT1A and 5-HT2A receptors.[A182186, A38385, A259661] Brexpiprazole was first approved by the FDA on July 10, 2015.
Categories: MATE 2 Inhibitors, Cytochrome P-450 SubstratesSynonyms: Lu-AF41156Hyoscyamine
go.drugbank.com/drugs/DB00424ApprovedInvestigational[A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic properties. … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine].[A228423] It is commonly extracted from plants in the _Solanaceae_ or nightshade family.
Mixtures: Uro-L, Me NaPhos MB Hyo 1Synonyms: L-Hyoscyamine, L-Tropine tropateDirithromycin
go.drugbank.com/drugs/DB00954InvestigationalDirithromycin is a macrolide glycopeptide antibiotic used to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsillitis, and even skin infections.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsSynonyms: (9S)-9-deoxo-11-deoxy-9,11-(imino((1R)-2-(2-methoxyethoxy)ethylidene)oxy)erythromycinDeucravacitinib
go.drugbank.com/drugs/DB16650ApprovedInvestigationalDeucravacitinib is a novel oral selective tyrosine kinase 2 (TYK2) inhibitor. … [A246938, A246943] This selectivity towards TYK2 may lead to an improved safety profile of deucravacitinib, as nonselective JAK inhibitors are associated with a range of adverse effects such as altered
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: SOTYKTU 6 mg film coated tablets, SOTYKTU® 6MG TABLETAS RECUBIERTASIotrolan
go.drugbank.com/drugs/DB09487ApprovedWithdrawnNonionic, isotonic contrast medium designed for intrathecal use.
Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Media, IodinatedInternational brands: Osmovist 190, Osmovist 240Ioxaglic acid
go.drugbank.com/drugs/DB09313ApprovedWithdrawnIoxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. … Ioxaglic acid has a low osmolarity and is associated with fewer side effects compared to older contrast agents [L1883].
Mixtures: Hexabrix 200, Hexabrix 200Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast ActivityFlumethasone
go.drugbank.com/drugs/DB00663ApprovedVet approvedAs it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. … This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.
Mixtures: LOCACORTENE VİOFORME 0,2 MG/G+30 MG/G KREM, 15 G, LOCACORTENE VİOFORME 0,2 MG/G+30 MG/G KREM, 30 GCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesHexaminolevulinate
go.drugbank.com/drugs/DB06261ApprovedInvestigationalof a prior cystoscopy. … On May 28, 2010, the U.S.
Synonyms: 4-Hexyloxycarbonyl-2-oxobutylammoniumchloride, Hexyl 5-amino-4-oxopentanoate hydrochlorideProducts: Hexvix 85 mg Pulver und Lösungsmittel zur Herstellung einer Lösung zur intravesikalen AnwendungMidostaurin
go.drugbank.com/drugs/DB06595ApprovedInvestigationalMidostaurin (as Rydapt) is a multitarget kinase inhibitor for the treatment for adult patients with newly diagnosed acute myeloid leukemia (AML) who have a specific genetic mutation called FLT3. … It was initially characterized as a potential broad-spectrum antineoplastic agent, with activity toward diverse solid and hematopoietic tumors [A19108].
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 InducersSynonyms: 4'-N-benzoylstaurosporineGanciclovir
go.drugbank.com/drugs/DB01004ApprovedInvestigationalAn acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Categories: MATE 1 Substrates, MATE 2 SubstratesSynonyms: 2-(6-Amino-purin-9-ylmethoxy)-propane-1,3-diol, 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1H-purin-6(9H)-one