Search
Infliximab
go.drugbank.com/drugs/DB00065ApprovedInvestigationalInfliximab was first approved by the FDA in 1998 under the market name Remicade as an intravenous injection. … Its hyperactivity and enhanced signalling pathways can be observed in inflammatory diseases where it activates further pro-inflammatory cascades.
Synonyms: IMMUNOGLOBULIN G (HUMAN-MOUSE MONOCLONAL CA2 HEAVY CHAIN ANTI-HUMAN TUMOR NECROSIS FACTOR), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL CA2 LIGHT CHAIN, DIMERCategories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsCP-12
go.drugbank.com/drugs/DB18169InvestigationalSynonyms: CYCLIZED P12 (PEPTIDE BOND BETWEEN THE CARBOXY AND AMINO-TERMINAL ENDS OF THE LINEAR PEPTIDE PSHISKYILRWRPK)Rituximab
go.drugbank.com/drugs/DB00073ApprovedInvestigationalThe antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences [A40017], [FDA label]. … It was originally approved by the U.S.
Categories: Amino Acids, Peptides, and Proteins, Monoclonal antibodies and antibody drug conjugatesProducts: MABTHERA 500MG/50ML VIALS, MABTHERA VIALS 500MG/50MLGolimumab
go.drugbank.com/drugs/DB06674ApprovedInvestigationalThus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with moderate to severe active rheumatoid arthritis (RA), (ii) alone or as an adjunct to methotrexate … Additionally in children and adolescents taking golimumab, there have been lymphoma and other malignancies observed.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: SIMPONI 100MG ILO IN FER, SIMPONI SOLUTION FOR INJECTION IN PRE-FILLED PEN 45MG/0.45MLGlycerin
go.drugbank.com/drugs/DB09462ApprovedInvestigationalA trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Mixtures: Cry for You Lubricant Eye Drops, Up and Up HemorrhoidalCategories: Compounds used in a research, industrial, or household setting, Alimentary Tract and MetabolismZonisamide
go.drugbank.com/drugs/DB00909ApprovedInvestigationalThe US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] … Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.
Categories: Calcium-Regulating Hormones and Agents, Compounds used in a research, industrial, or household settingProducts: ZONEGRAN 25MG, ZONISOL 20MG/ML SUECalcium ascorbate
go.drugbank.com/drugs/DB14483ApprovedNutraceuticalMixtures: Calcium Ascorbate Cap 850mg, Calcium Ascorbate Cap 850mgCategories: Compounds used in a research, industrial, or household setting, Vitamin C and analoguesFlupentixol
go.drugbank.com/drugs/DB00875ApprovedInvestigationalWithdrawnIt is approved for use in Canada and other countries around the world, but not in the US. … [A229083] Flupentixol is an antagonist of both D1 and D2 dopamine receptors.
Products: Fluanxol Depot Inj 100mg/ml, Fluanxol Depot 10%- Liq Im 100mg/mlHydrochlorothiazide
go.drugbank.com/drugs/DB00999ApprovedInvestigationalVet approved[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors. … Hydrochlorothiazide is the most commonly prescribed thiazide diuretic.[A185138] It is indicated to treat edema and hypertension.
Mixtures: ENABETA COMP 10MG/25MG, BISOBETA COMP 10MG/25MGCategories: hydrochlorothiazide and potassium, Genito Urinary System and Sex HormonesEtanercept
go.drugbank.com/drugs/DB00005ApprovedInvestigational[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. … Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids.
Categories: Amino Acids, Peptides, and ProteinsProducts: BENEPALI 25MG ILO IN FER, ERELZI 25MG ILO IN FER