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Displaying results 231 - 240 of 9347 in total
  1. Drug

    Baricitinib

    go.drugbank.com/drugs/DB11817
    ApprovedInvestigational

    [A248400] The EC later approved baricitinib for the treatment of atopic dermatitis, making it the first JAK inhibitor used for this indication in Europe. … [L41760] Baricitinib was first approved by the European Commission (EC) in February 2017 for the treatment of rheumatoid arthritis in adults [A248395] and was later approved by the FDA in 2018.

  2. Drug

    Carteolol

    go.drugbank.com/drugs/DB00521
    Approved

    A beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.

  3. Drug

    Urea

    go.drugbank.com/drugs/DB03904
    ApprovedInvestigational

    A compound formed in the liver from ammonia produced by the deamination of amino acids. … It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.

    Mixtures: Ti-U-lac Lotion, Ti-U-lac HC LotionProducts: Uramaxin TS, RE Urea
  4. Drug

    Demecarium

    go.drugbank.com/drugs/DB00944
    Approved

    The outflow of the aqueous humor is facilitated, which leads to a reduction in intraocular pressure. … In the eye, this causes constriction of the iris sphincter muscle (causing miosis) and the ciliary muscle.

  5. Drug

    Olopatadine

    go.drugbank.com/drugs/DB00768
    Approved

    An ophthalmic solution of olopatadine was approved by the FDA and European Union for the treatment of seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. … [L6790] Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and allergic reactions.

    Products: TQ OLOFTAL® 0.2% SOLUCION OFTALMICA
  6. Drug

    Talc

    go.drugbank.com/drugs/DB09511
    ApprovedInvestigational

    Although talc has been widely used for decades, lawsuits that have come to the surface claim serious health complications linked to its use. … Talc helps absorb moisture, freshen materials, and reduce friction to prevent rashes.

    Synonyms: E-553(III)
  7. Drug

    Levobetaxolol

    go.drugbank.com/drugs/DB09351
    Approved

    Levobetaxolol is a beta-blocker used to lower the pressure in the eye to treat conditions such as glaucoma. … It was marketed as a 0.5% ophthalmic solution of levobetaxolol hydrochloride under the trade name Betaxon but has been discontinued.

  8. Drug

    Diltiazem

    go.drugbank.com/drugs/DB00343
    ApprovedInvestigational

    specificity to target both the cardiac and vascular smooth muscle. … Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class.

    Products: Diltiazem T, Diltiazem TZ
  9. Drug

    Moxifloxacin

    go.drugbank.com/drugs/DB00218
    ApprovedInvestigational

    Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.

    Mixtures: TQ OFTAMOX D UD®, TQ OFTAMOX® D UDProducts: T & B, TQ OFTAMOX® UD
  10. Drug

    Etoposide

    go.drugbank.com/drugs/DB00773
    ApprovedInvestigational

    Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.

    Products: VP-TEC, EPOSIN CONCENTRADO PARA SOLUCION DE INFUSION DE 20 MG/ML