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Displaying results 231 - 240 of 10000 in total
  1. Drug

    Lacosamide

    go.drugbank.com/drugs/DB06218
    ApprovedInvestigational

    [A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved by the FDA in October 2008. … [A262681] It was granted approval by Health Canada in September 2010.[L49206]

    Synonyms: (R)-2-acetamido-N-benzyl-3- methoxypropionamide, (+)-(2R)-2-(ACETYLAMINO)-N-BENZYL-3-METHOXYPROPANAMIDEProducts: APILEP® 100MG, LACOSAMIDA 100MG
  2. Drug

    Zolpidem

    go.drugbank.com/drugs/DB00425
    ApprovedInvestigational

    Zolpidem, also known as _Ambien_, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. … In addition, zolpidem improves sleep quality in patients suffering from chronic insomnia and can show mild muscle relaxant properties [L5584].

    Synonyms: N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamideProducts: ZOLPIDEM EG, Zolpidem Tartrate ER
  3. Drug

    Bupropion

    go.drugbank.com/drugs/DB01156
    ApprovedInvestigational

    [A178816] Bupropion is sometimes used as an add-on agent to first-line treatments of depression such as selective serotonin reuptake inhibitor (SSRI) medications when there is a treatment-failure or … While it has comparable effectiveness to typical first-line options for the treatment of depression such as SSRIs,[A178798,A178804] bupropion is a unique option for the treatment of MDD as it lacks any

    Products: Aplenzin ER, MEJYA ER
  4. Drug

    Hydrochlorothiazide

    go.drugbank.com/drugs/DB00999
    ApprovedInvestigationalVet approved

    [L7426,L7459] Hydrochlorothiazide was granted FDA approval on 12 February 1959.[L8444] … [A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors.

    Mixtures: LOSARPLUS AL 100MG/25MG, LOSARPLUS AL 100MG/25MGProducts: Hydrodiuril Tab 100mg, Hydrochlorothiazide 100mg Tablets
  5. Drug

    Daratumumab

    go.drugbank.com/drugs/DB09331
    ApprovedInvestigational

    In July 2024, it was further approved in combination with bortezomib, lenalidomide, and dexamethasone (D-VRd) for induction and consolidation therapy in newly diagnosed, transplant-eligible patients. … [A7935] It was first described in the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of its kind.

    Products: DARZALEX CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/5ML, DARZALEX SC SOLUTION FOR INJECTION 1800MG/15ML
  6. Drug

    Brinzolamide

    go.drugbank.com/drugs/DB01194
    Approved

    [L35310,L35315] In Europe, it was also approved as a combination product with timolol in 2008.[L35320] … [A2049,A2051] Although systemic anti-carbonic anhydrase (CA) therapy has been used for almost 50 years with varying degrees of success, systemic administration results in an increase in incidences of adverse

    Mixtures: AZARGA 10MG/ML+5MG/ML, AZARGA 10MG/ML + 5MG/MLProducts: BRINZOLAMIDE EG, AZOPT 10MG/ML
  7. Drug

    Panthenol

    go.drugbank.com/drugs/DB11204
    Approved

    Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. … that are important for protein metabolism in the epithelium [A32373].

    Mixtures: EH Plus H2CO3 Cool, EH Plus H2CO3 CoolProducts: BABOR BODY LINE THERMAL Firming Body, Babor Body Line Thermal Smooth Effect Body
  8. Drug

    Enalapril

    go.drugbank.com/drugs/DB00584
    ApprovedInvestigationalVet approved

    The active metabolite enalaprilat is also available in oral tablets and intravenous formulations for injection. … It is also found in a combination product containing [hydrochlorothiazide] that is used for the management of hypertension.

    Mixtures: ENA LERCA OMNIAPHAR10/10MG, ENA LERCA OMNIAPHAR10/10MGCategories: Agents Acting on the Renin-Angiotensin System
  9. Drug

    Nitroglycerin

    go.drugbank.com/drugs/DB00727
    ApprovedInvestigational

    Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent [L38369] that was first discovered in 1847. … [A249970] Nitroglycerin causes vasodilation in both arteries and veins.

    International brands: Gen-NitroMixtures: Nitroglycerin In 5% Dextrose Inj.-100mcg/ml, NITROGLICERINA 0.1 MG/ML EN DEXTROSA 5% SOLUCION INYECTABLE
  10. Drug

    Phenolphthalein

    go.drugbank.com/drugs/DB04824
    ApprovedWithdrawn

    Phenolphthalein was withdrawn in Canada due to concerns with carcinogenicity in 1997.

    Mixtures: EX-lax Light Formula Lax W Stool Soften TabCategories: Compounds used in a research, industrial, or household setting