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Thioridazine
go.drugbank.com/drugs/DB00679ApprovedWithdrawnIt has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. … Thioridazine was withdrawn worldwide in 2005 due to its association with cardiac arrythmias.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsSynonyms: 10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazine, 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazineNitrofurantoin
go.drugbank.com/drugs/DB00698ApprovedInvestigationalVet approved[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. … [A179830] Nitrofurantoin was granted FDA approval on 6 February 1953.[L6895]
Synonyms: 5-Nitrofurantoin, 1-((5-nitrofurfurylidene)amino)hydantoinProducts: PIYELOSEPTYL 25 MG/5 ML ORAL SUSPANSIYON, 100 ML, PIYELOSEPTYL 100 MG TABLET, 30 ADETSildenafil
go.drugbank.com/drugs/DB00203ApprovedInvestigationalIn eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850 … Although the medication has historically been most popularly recognized as Pfizer's brand name Viagra, sildenafil is currently available generically and even as a non-prescription over the counter medication
Mixtures: DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLET, DAPOKSEL 30 MG/50 MG FILM TABLET ,6 FILM TABLETCategories: Phosphodiesterase 5 Inhibitors, Cytochrome P-450 SubstratesPhenytoin
go.drugbank.com/drugs/DB00252ApprovedInvestigationalVet approved[A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications … such as bipolar disorder, retina protection, and wound healing.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 SubstratesProducts: Epilan-D 50 mg/ml - Ampullen, EPAMIN® PARENTERICO 50 MG/ML X 5 MLLidocaine
go.drugbank.com/drugs/DB00281ApprovedInvestigationalVet approvedAs a result, lidocaine is also considered a class Ib anti-arrhythmic agent [L5930, L5948, F4468]. … Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication [T583].
Mixtures: MIXOVUL 750 MG/200 MG/100 MG OVÜL, 7 OVÜL, DENTINOX 3.4 MG/G + 3.2 MG/G + 150 MG/G JEL, 10 GCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsSulpiride
go.drugbank.com/drugs/DB00391ApprovedWithdrawnSulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher d...
Synonyms: N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide, N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamideProducts: MERESA 50 MG KAPSUL, 100 ADET, DOLPIRID 100 MG/2 ML AMPUL, 6 ADETTirofiban
go.drugbank.com/drugs/DB00775ApprovedInvestigationalTirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. It is a non-peptide reversible antagonist of the platelet glyc...
Products: AGREDUR READY 50 MCG/ML I.V. İNFÜZYON İÇİN ÇÖZELTİ, 100 ML, ROFİSTAT 12.5 MG/50 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN FLAKONIodixanol
go.drugbank.com/drugs/DB01249ApprovedIodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the
Synonyms: 5,5'-((2-hydroxytrimethylene)bis(acetylimino))bis(N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide)Products: VISIPAQUE 270 MG/ML IA IV İNTRATEKAL ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN FLAKON, 50 ML, VISIPAQUE 320 MG/ML IA IV İNTRATEKAL ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN FLAKON, 50 MLDoxycycline
go.drugbank.com/drugs/DB00254ApprovedInvestigationalVet approved[L42880] It is a second-generation tetracycline that was first discovered in 1967.[A19429] Second-generation tetracyclines exhibit lesser toxicity than first-generation tetracyclines.
Mixtures: BenzoDox 30 Kit, BenzoDox 60 KitCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsNetilmicin
go.drugbank.com/drugs/DB00955ApprovedNetilmicin is a semisynthetic 1-N-ethyl derivative of sisomycin, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity. Netilmicin inhibits protein synthesis in susceptible organisms by binding ...
Mixtures: NETİZON 5 MG+15 MG/5 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET, NETILDEX GOZ DAMLASI %0,1 DEKSAMETAZON + %0,3 NETILMISIN 5 MLProducts: NELIN 100 MG / 2ML INJECTION, NELIN 150 MG/ 1.5 ML INJECTION