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Displaying results 2411 - 2420 of 10000 in total
  1. Drug

    Plerixafor

    go.drugbank.com/drugs/DB06809
    ApprovedInvestigational

    [A7117,L45678] It is used to stimulate the release of stem cells from the bone marrow into the blood in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma to stimulate their immune system. … Since CXCR4 and SDF-1α are involved in the trafficking and homing of CD34+ cells to the marrow compartment, blocking this interaction leads to an increase in CD34+ cell circulating levels.

    Products: AUROPLERISTEM 20 MG/ML, Mozobil 20 mg/ml solution for injection
  2. Drug

    Esterified estrogens

    go.drugbank.com/drugs/DB09381
    Approved

    It is being also for the prevention and treatment of osteoporosis. … Esterified estrogens contain a mixture of estrogenic substances; the principle component is estrone.

  3. Drug

    Osilodrostat

    go.drugbank.com/drugs/DB11837
    ApprovedInvestigational

    [L12123] It is used to lower circulating cortisol levels in the treatment of Cushing's disease, a disorder in which cortisol levels are chronically and supraphysiologically elevated. … [L12123] It has undergone phase II clinical trials for the treatment of solid tumours, hypertension, and heart failure, but development for these indications was discontinued by Novartis in January 2013

  4. Drug

    Sotrovimab

    go.drugbank.com/drugs/DB16355
    ApprovedInvestigational

    [L41369] Sotrovimab was granted marketing authorization in the European Union in December 2021 under the brand name Xevudy.[L39625,L39620] … high-risk adults with COVID-19 in the outpatient setting.

  5. Drug

    Benfluorex

    go.drugbank.com/drugs/DB09022
    ApprovedWithdrawn

    Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine. It was patented and manufactured by a French pharmaceutical company Servier.

    Categories: Drugs Used in Diabetes
  6. Drug

    Voglibose

    go.drugbank.com/drugs/DB04878
    Investigational

    It is made in India by Ranbaxy Labs and sold under the trade name Volix. … Voglibose is an alpha-glucosidase inhibitor used for lowering post-prandial blood glucose levels in people with diabetes mellitus.

    Categories: Drugs Used in Diabetes
  7. Drug

    Alverine

    go.drugbank.com/drugs/DB01616
    ApprovedInvestigationalWithdrawn

    Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. … It can also be used to help relieve period pain.

  8. Drug

    Droxicam

    go.drugbank.com/drugs/DB09215
    ApprovedWithdrawn

    It is used to reduce pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. … Droxicam is an oxicam non-steroidal anti-inflammatory drug and a prodrug of [DB00554].

  9. Drug

    Metyrapone

    go.drugbank.com/drugs/DB01011
    ApprovedInvestigational

    It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome.

  10. Drug

    Carboprost tromethamine

    go.drugbank.com/drugs/DB00429
    ApprovedInvestigational

    A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.

    Products: HEMABATE INJECTION 250 mcg/ml, HEMABATE STERILE SOLUTION 250MCG/ML