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DB09022ApprovedWithdrawnSmall molecule
Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine. It was patented and manufactured by a French pharmaceutical company Servier. The European Medicines Agency (EMA) recommended... This recommendation was based on the risks (especially fenfluramine-like cardiovascular side-effects) outweighing the benefits.
- Mechanism
- Curator reviewed
Pharmacologically active on Sterol O-acyltransferase 1
- Formula / weight
- C19H20F3NO2 · 351.3628 g/mol (avg)
- Code names
- JP 992 · S 780 · SE 780
Resolves to
Clinical / RWD
Structure
InChIKey
CJAVTWRYCDNHSM-UHFFFAOYSA-NSMILESCC(CC1=CC(=CC=C1)C(F)(F)F)NCCOC(=O)C1=CC=CC=C1Targets
What you can answer from here — as of August 30, 2026
1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
Which drugs share a target with Benfluorex, and which of those have an active Phase 3 trial?