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Varespladib methyl
go.drugbank.com/drugs/DB05737InvestigationalVarespladib methyl has been investigated for the treatment of Acute Coronary Syndrome.
Ruxolitinib
go.drugbank.com/drugs/DB08877ApprovedInvestigational[A229938] Ruxolitinib was first approved for the treatment of adult patients with myelofibrosis by the FDA in 2011, followed by EMA's approval in 2012. … [A229708] In 2014, it was approved for the treatment of polycythemia vera in adults who have an inadequate response to or are intolerant of [hydroxyurea] and in 2019, ruxolitinib was approved for use in
Categories: Agents for Dermatitis, Excluding CorticosteroidsAlitretinoin
go.drugbank.com/drugs/DB00523ApprovedTretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic. … It has also been approved for use in promyelocytic leukemia (leukemia, promyelocytic, acute).
Categories: Retinoids for cancer treatment, Agents for Dermatitis, Excluding CorticosteroidsMephentermine
go.drugbank.com/drugs/DB01365ApprovedWithdrawn(From Martindale, The Extra Pharmacopoeia, 30th ed, p1248) … It is used to maintain blood pressure in hypotensive states, for example, following spinal anesthesia.
Sulfacetamide
go.drugbank.com/drugs/DB00634ApprovedAn anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Categories: Anti-Acne Preparations for Topical Use, Antiinfectives for Treatment of AcneAcalabrutinib
go.drugbank.com/drugs/DB11703ApprovedInvestigationalIt also received Orphan Drug designation, which provides incentives to assist and encourage the development of drugs for rare diseases. … Continued approval for acalabrutinib's currently accepted indication may subsequently be contingent upon ongoing verification and description of clinical benefit in confimatory trials.
Colestipol
go.drugbank.com/drugs/DB00375Approvedbiliary obstruction, etc. may not be good candidates for using the agent owing to its physical effects on the gut. … [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia
Categories: Hypolipidemic Agents Indicated for Hyperlipidemia, Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaDonepezil
go.drugbank.com/drugs/DB00843ApprovedInvestigationalDonepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. … [L7916,L7937] A donepezil transdermal delivery system, Adlarity, was approved by the FDA in March 2022 for the treatment of Alzheimer's dementia.
Eflapegrastim
go.drugbank.com/drugs/DB15001ApprovedInvestigational[L43135] In September 2022, eflapegrastim was approved by the US FDA as a prophylactic against infection, as manifested by febrile neutropenia, in patients receiving certain myelosuppressive anti-cancer … [L43135] Eflapegrastim is a form of recombinant human G-CSF comprising a human G-CSF analog coupled to the Fc fragment of human IgG4 via a polyethylene glycol linker.
Starch, corn
go.drugbank.com/drugs/DB11599ApprovedInvestigationalNutraceuticalStarch is the chief storage form of energy reserve (carbohydrates) in plants. … Starch is any of a group of polysaccharides of the general formula (C6-H10-O5)n, composed of a long-chain polymer of glucose in the form of amylose and amylopectin.
Categories: Compounds used in a research, industrial, or household setting