Search
Cidofovir
go.drugbank.com/drugs/DB00369ApprovedInvestigationalCidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. … [FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since been discontinued.[L6223]
Synonyms: ({[(S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid, (S)-(3-(4-amino-2-Oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acidCategories: Heterocyclic Compounds, 1-RingMoxifloxacin
go.drugbank.com/drugs/DB00218ApprovedInvestigationalBayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment. … Moxifloxacin is a synthetic fluoroquinolone antibiotic agent.
Mixtures: Ixoba M, TQ OFTAMOX D UD®Categories: 4-Quinolones, Heterocyclic Compounds, 2-RingCodeine
go.drugbank.com/drugs/DB00318ApprovedIllicitInvestigationalCodeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory … The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities.
Mixtures: M-end Max D, M-end WcCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAcetylcysteine
go.drugbank.com/drugs/DB06151ApprovedInvestigational[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results. … [A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.[L31488]
Synonyms: N-AC, N Acetyl L CysteineMixtures: AMINOPLASMAL-5% E INFUSION, MUCOFIX 600/200 MG EFERVESAN, 5 ADETIpilimumab
go.drugbank.com/drugs/DB06186ApprovedInvestigational[L12126] Ipilimumab was granted FDA approval on 25 March 2011.[L12126] … [L12126] Blocking CTLA-4 removes an inhibitory signal from reducing the activity of T lymphocytes.[A35065,A35080,L12126] Ipilimumab was developed by Bristol-Myers Squibb and Medarex.
Categories: Immunoglobulin G, CTLA-4-directed Blocking AntibodyProducts: YERVOY®5 MG /ML SOLUCION INYECTABLE PARA INFUSION INTRAVENOSA, YERVOY 5 mg/ml concentrate for solution for infusionIbuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigational[A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. … [A39076] On the available products, ibuprofen is administered as a racemic mixture.
Synonyms: (±)-α-methyl-4-(2-methylpropyl)benzeneacetic acid, (±)-2-(p-isobutylphenyl)propionic acidInternational brands: Act-3, Alges-XEtelcalcetide
go.drugbank.com/drugs/DB12865ApprovedInvestigationalEtelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. … Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.
Products: PARSABIV SOLUTION FOR INJECTION 5 mg/mL, PARSABİV 5 MG/1 ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 1 ADETNaproxen
go.drugbank.com/drugs/DB00788ApprovedInvestigationalVet approved[A179098] Given its overall tolerability and effectiveness, naproxen can be considered a first line treatment for a variety of clinical situations requiring analgesia. … Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994.
Synonyms: (+)-(S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid, (S)-2-(6-Methoxy-2-naphthyl)propanoic acidInternational brands: Bumaflex N, Naprosyn ECIsoprenaline
go.drugbank.com/drugs/DB01064ApprovedInvestigationalIsoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion … [A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and a stronger action than [adrenaline].
Categories: Compounds used in a research, industrial, or household setting, Adrenergic beta-2 Receptor AgonistsSynonyms: N-Isopropylnoradrenaline, N-IsopropylnorepinephrinePerindopril
go.drugbank.com/drugs/DB00790ApprovedInvestigationalIt is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. … Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).
Mixtures: Triveram 10 mg/5 mg/5 mg Filmtabletten, Triplixam 5 mg/1,25 mg/5 mg FilmtablettenCategories: Heterocyclic Compounds, 2-Ring, Agents Acting on the Renin-Angiotensin System