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Displaying results 2451 - 2460 of 10000 in total
  1. Drug

    Desloratadine

    go.drugbank.com/drugs/DB00967
    ApprovedInvestigational

    It is the active descarboethoxy metabolite of loratidine (a second generation histamine). … Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action.

    Synonyms: 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridineMixtures: DESCASE 5 MG / 10 MG FILM KAPLI TABLET ,90 ADET, DESCASE 5 MG / 10 MG FILM KAPLI TABLET ,30 ADET
  2. Drug

    Icatibant

    go.drugbank.com/drugs/DB06196
    ApprovedInvestigational

    Icatibant is a synthetic decapeptide with 5 nonproteinogenic amino acid antagonist targeting the B<sub>2</sub> receptors with a similar affinity to bradykinin. … [A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema.

    Categories: Drugs Used in Hereditary AngioedemaProducts: Icatibant Reddy 30 mg/3 ml Injektionslösung in einer Fertigspritze, Icatibant STADA 30 mg Injektionslösung in einer Fertigspritze
  3. Drug

    Protamine

    go.drugbank.com/drugs/DB13700
    ApprovedInvestigationalWithdrawn

    Products: PROTAMYN 1000® UI/ML AMPOLLA, PROTAMİN ICN 5000 IU/5ML IV KULLANIM İÇİN ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 50 ADET
  4. Drug

    Ferric derisomaltose

    go.drugbank.com/drugs/DB15617
    ApprovedInvestigational

    [A190528] Ferric derisomaltose is a form of iron used in the treatment of iron deficiency. This drug is a complex of iron (III) hydroxide and derisomaltose. … [L11581,L11587] Clinical trials show that it is non-inferior to [iron sucrose], another form of iron that is often administered in iron deficiency, and less likely to cause serious hypersensitivity that

    Products: Monofer 100 mg/ml solution for injection/infusion in vials, Diafer 50 mg/ml Injektionslösung
  5. Drug

    Antilymphocyte immunoglobulin (horse)

    go.drugbank.com/drugs/DB09312
    ApprovedInvestigational

    Induction of T cell apoptosis and resulting T-cell lymphopenia found in vivo is credited for its therapeutic effect in these conditions. … It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen.

    Synonyms: e-ATG, h-ATGCategories: Immunoglobulin G, Increased T Lymphocyte Destruction
  6. Drug

    Acetylcysteine

    go.drugbank.com/drugs/DB06151
    ApprovedInvestigational

    Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of [acetaminophen] overdose. … [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.

    Synonyms: N-AC, N Acetyl L CysteineMixtures: AMINOPLASMAL 15% IN 500ML GLASS BOTTLE, MUCOFIX 600/200 MG EFERVESAN, 5 ADET
  7. Drug

    Levocetirizine

    go.drugbank.com/drugs/DB06282
    ApprovedInvestigational

    [L7694] Levocetirizine has greater affinity for the histamine H<sub>1</sub> receptor than cetirizine.[L7694] Levocetirizine was granted FDA approval in 1995.[L7694] … Levocetirizine is a selective histamine H<sub>1</sub> antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of [cetirizine].

    Synonyms: 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acidMixtures: BROCRIPTIN® 10 MG/ 5 MG, LEPIXOS 5 MG/10 MG FILM TABLET ,30 ADET
  8. Drug

    Levosimendan

    go.drugbank.com/drugs/DB00922
    ApprovedInvestigationalWithdrawn

    Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels. … Levosimendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure).

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingProducts: SİMELEV 12,5 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, SIMDAX 2.5 MG/ML KONSANTRE INF.COZ.5 ML X FLAKON, 1 ADET
  9. Drug

    Pantoprazole

    go.drugbank.com/drugs/DB00213
    ApprovedInvestigational

    in hypersecretion. … As the binding of pantoprazole to the (H+, K+)-ATPase enzyme is irreversible and new enzyme needs to be expressed in order to resume acid secretion, pantoprazole's duration of antisecretory effect persists

    Mixtures: OCAM® DUO.Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
  10. Drug

    Licaminlimab

    go.drugbank.com/drugs/DB18936
    Investigational

    Licaminlimab is under investigation in clinical trial NCT05896670 (Safety and Efficacy of Licaminlimab Ophthalmic Suspension for the Treatment of Dry Eye Disease).

    Synonyms: immunoglobulin scFv, anti-[Homo sapiens TNF (tumor necrosis factor, TNFSF2, DIF, TNF-alpha)], humanized monoclonal antibody single chain; IG scFv humanized single chain (V-KAPPA-VH) (1-254) [V-KAPPA (Homo, sapiens IGKV1-5*03 (79.2%) -(IGHD) -IGKJ2*02 (77.