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Genipin
go.drugbank.com/drugs/DB19124InvestigationalGenipin is under investigation in clinical trial NCT05755750 (Intratendinous Genipin Injection in Horses With Tendon Injuries).
Synonyms: Cyclopenta(c)pyran-4-carboxylic acid, 1,4a,5,7a-tetrahydro-1-hydroxy-7-(hydroxymethyl)-, methyl ester, (1r-(1.alpha.,4a.alpha.,7a.alpha.))-, Cyclopenta(c)pyran-4-carboxylic acid, 1,4a,5,7a-tetrahydro-1-hydroxy-7-(hydroxymethyl)-, methyl ester, (1r,4as,7as)-Categories: Heterocyclic Compounds, 1-RingGiredestrant
go.drugbank.com/drugs/DB19125InvestigationalGiredestrant is under investigation in clinical trial NCT06065748 (A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With Er-positive
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: (1r,3r)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)-3-azetidinyl)amino)phenyl)-.beta.,.beta.-difluoro-1,3,4,9-tetrahydro-3-methyl-2h-pyrido(3,4-b)indole-2-propanol, 3-((1r,3r)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2h-pyrido(3,4-b)indol-2-yl)-2,2-difluoropropan-1-olNUC-7738
go.drugbank.com/drugs/DB19148InvestigationalNUC-7738 is under investigation in clinical trial NCT03829254 (A Safety, Pharmacokinetic and Clinical Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma).
Categories: Heterocyclic Compounds, 2-RingSynonyms: L-Alanine, N-(3′-deoxy-P-phenyl-5′-adenylyl)-, phenylmethyl ester (ACI)p-Boronophenylalanine
go.drugbank.com/drugs/DB19158Investigationalp-Boronophenylalanine is under investigation in clinical trial NCT00039572 (Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the Brain).
Synonyms: 4-borono-l-phenylalanine, L-p-boronophenylalaninePudexacianinium
go.drugbank.com/drugs/DB19161InvestigationalPudexacianinium is under investigation in clinical trial NCT05754333 (A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery).
Synonyms: -cyclodextrin, 2a-o-(3-aminopropyl)-, diamide with 3-(2-carboxyethyl)-2-(2-(3-(2-(3-(2-carboxyethyl)-1,3-dihydro-1,1-dimethyl-2h-benz(e)indol-2-ylidiene)ethylidene)-2-methoxy-1-cyclohexen-1-yl)ethylene, 3-(3-((3-(CYCLOMALTOHEPTAOS-21-O-YL)PROPYL)AMINO)-3-OXOPROPYL)-2-((1E)-2-((3E)-3-((2E)-2-(3-(3-((3-(CYCLOMALTOHEPTAOS-21-O-YL)PROPYL)AMINO)-3-OXOPROPYL)-1,1-DIMETHYL-1,3-DIHYDRO-2H-BENZO(E)INDOL-2-YLIDENEPirepemat
go.drugbank.com/drugs/DB19165InvestigationalPirepemat is under investigation in clinical trial NCT05258071 (A Clinical Study Evaluating Efficacy of Pirepemat on Falls Frequency in Patients With Parkinson's Disease (PD)).
Synonyms: (3s)-3-(2,3-difluorophenyl)-3-methoxypyrrolidine, Pyrrolidine, 3-(2,3-difluorophenyl)-3-methoxy-, (+)-Pemrametostat
go.drugbank.com/drugs/DB19170InvestigationalPemrametostat is under investigation in clinical trial NCT03614728 (Study to Investigate the Safety and Clinical Activity of GSK3326595 and Other Agents to Treat Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)).
Synonyms: 4-pyrimidinecarboxamide, 6-((1-acetyl-4-piperidinyl)amino)-n-((2s)-3-(3,4-dihydro-2(1h)-isoquinolinyl)-2-hydroxypropyl)-, 6-((1-acetyl-4-piperidinyl)amino)-n-((2s)-3-(3,4-dihydro-2(1h)-isoquinolinyl)-2-hydroxypropyl)-4-pyrimidinecarboxamideCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingGonyautoxin II
go.drugbank.com/drugs/DB19186InvestigationalGonyautoxin II is under investigation in clinical trial NCT04799041 (Gonyautoxin 2/3 in the Treatment of Acute Back Pain: A Clinical Proof-of-concept Study).
Categories: Heterocyclic Compounds, 2-Ring, Complex MixturesSynonyms: 1h,10h-pyrrolo(1,2-c)purine-9,10,10-triol, 2,6-diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-, 9-(hydrogen sulfate), (3as-(3a.alpha.,4.alpha.,9.beta.,10ar*))- 11.alpha., Gonyautoxin 2ABBV-744
go.drugbank.com/drugs/DB19199InvestigationalSynonyms: 1H-PYRROLO(2,3-C)PYRIDINE-2-CARBOXAMIDE, N-ETHYL-4-(2-(4-FLUORO-2,6-DIMETHYLPHENOXY)-5-(1-HYDROXY-1-METHYLETHYL)PHENYL)-6,7-DIHYDRO-6-METHYL-7-OXO-, N-ethyl-4-(2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl)-6-methyl-7-oxo-6,7-dihydro-1h-pyrrolo(2,3-c)pyridine-2-carboxamideCategories: Heterocyclic Compounds, 1-RingAcoltremon
go.drugbank.com/drugs/DB19202ApprovedInvestigationalAcoltremon is under investigation in clinical trial NCT05493111 (A Long-term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512).
Synonyms: Cyclohexanecarboxamide, n-(4-methoxyphenyl)-5-methyl-2-(1-methylethyl)-, (1r,2s,5r)-, N-(4-methoxyphenyl)-5-methyl-2- (1-methylethyl)cyclohexanecarboxamide, (1r,2s,5r)-