p-Boronophenylalanine
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- p-Boronophenylalanine
- DrugBank Accession Number
- DB19158
- Background
p-Boronophenylalanine is under investigation in clinical trial NCT00039572 (Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the Brain).
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 209.01
Monoisotopic: 209.085938 - Chemical Formula
- C9H12BNO4
- Synonyms
- 4-borono-l-phenylalanine
- Borofalan
- L-p-boronophenylalanine
- L-phenylalanine, 4-borono-
- External IDs
- L-BPA
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- JSM63LV5MD
- CAS number
- 76410-58-7
- InChI Key
- NFIVJOSXJDORSP-QMMMGPOBSA-N
- InChI
- InChI=1S/C9H12BNO4/c11-8(9(12)13)5-6-1-3-7(4-2-6)10(14)15/h1-4,8,14-15H,5,11H2,(H,12,13)/t8-/m0/s1
- IUPAC Name
- SMILES
- N[C@@H](CC1=CC=C(C=C1)B(O)O)C(O)=O
References
- General References
- Not Available
- External Links
- ChemSpider
- 132497
- ChEMBL
- CHEMBL125582
- ZINC
- ZINC000169743223
- PDBe Ligand
- 7N8
- PDB Entries
- 5mhh / 5n5u / 6qmu / 7lqo / 8qdf
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at July 05, 2024 16:45 / Updated at July 06, 2024 06:45