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Trimetazidine
go.drugbank.com/drugs/DB09069ApprovedInvestigational[A233215] It is hypothesized that trimetazidine inhibits 3-ketoacyl coenzyme A thiolase, which decreases fatty acid oxidation but not glucose metabolism, preventing the acidic conditions that exacerbate … [L33015] Trimetazidine has been studied as a treatment for angina pectoris since the late 1960s.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-[2,3,4-trimethoxybenzyl] piperazine dihydrochlorideCefadroxil
go.drugbank.com/drugs/DB01140ApprovedInvestigationalVet approvedWithdrawnLong-acting, broad-spectrum, water-soluble, cephalexin derivative.
Categories: Heterocyclic Compounds, 2-RingSynonyms: D-CefadroxilCanakinumab
go.drugbank.com/drugs/DB06168ApprovedInvestigationalCanakinumab is a recombinant, human anti-human-IL-1β monoclonal antibody that belongs to the IgG1/κ isotype subclass. … It is expressed in a murine Sp2/0-Ag14 cell line and comprised of two 447- (or 448-) residue heavy chains and two 214-residue light chains, with a molecular mass of 145157 Daltons when deglycosylated.
Categories: Interleukin-1 BlockersProducts: ILARIS® SOLUCIÓN INYECTABLE 150 MG/ ML, İLARİS 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADETBexarotene
go.drugbank.com/drugs/DB00307ApprovedInvestigationalBexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: 4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid, 4-[1-(5,6,7,8,-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphtalenyl)ethenyl]benzoic acidMebeverine
go.drugbank.com/drugs/DB12554ApprovedInvestigationalWithdrawnMebeverine has been investigated for the treatment of Irritable Bowel Syndrome and Post-cholecystectomy Gastrointestinal Spasms.
Products: DUSPATALIN 100 MG KAPLI TABLET, 50 ADET, DUSPATALIN LIKIT 10 MG/ML, 250 MLAgalsidase beta
go.drugbank.com/drugs/DB00103ApprovedInvestigationalAgalsidase beta is a recombinant human α-galactosidase A similar to [agalsidase alfa]. … [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009.
Products: FABRAZYME 35 MG İNFÜZYONLUK ÇÖZELTİ İÇİN KONSANTRE TOZ, 1 ADET, ฟาบราไซม์ (5 มก.)Amorolfine
go.drugbank.com/drugs/DB09056ApprovedWithdrawnIt is available in the form of a 5% amorolfine nail lacquer used to treat onychomycosis (fungal infection of the toe- and fingernails). … Amorolfine 5% nail lacquer in once or twice weekly applications is 60-71% effective in treating toenail onychomycosis; complete cure rates three months after stopping treatment (after six months of treatment
Categories: Heterocyclic Compounds, 1-RingProducts: Amorocutan 50 mg/ml wirkstoffhaltiger Nagellack, Exorolfin 50 mg/ml - wirkstoffhaltiger NagellackDextromethorphan
go.drugbank.com/drugs/DB00514ApprovedInvestigational[A215412] Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997] … Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse.
Synonyms: D-methorphanMixtures: BENICAL 10 MG+20MG+2MG/5 ML SURUP, 100 ML, DAYCOLD-HOT 500/10/15/100 MG SAŞE,6 SAŞECyproterone acetate
go.drugbank.com/drugs/DB04839ApprovedInvestigationalIt is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Synonyms: Cyproterone 17-O-acetateMixtures: DIANE 2 MG/35 MCG KAPLI TABLET, 21 ADET, DONABELLA® 2 MG /0.035 MGOlopatadine
go.drugbank.com/drugs/DB00768ApprovedIt is a structural analog of [doxepin], which has a minimal anti-allergic activity. … Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions.
Mixtures: OFNOL FRESH % 0.1 + %0.15 STERİL OFTALMİK ÇÖZELTİ, 1 ADETCategories: Heterocyclic Compounds, 3-Ring, Cytochrome P-450 Substrates