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Seladelpar
go.drugbank.com/drugs/DB12390ApprovedInvestigational[L51149] On August 14, 2024, seladelpar was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis,[L51154] which is a condition associated with aberrant bile acid metabolism … Seladelpar is a single enantiomer of the R-configuration.
BMS-986020
go.drugbank.com/drugs/DB14948InvestigationalBMS-986020 is under investigation in clinical trial NCT02017730 (To Evaluate The Relationship Between Plasma Drug Levels And Receptor Binding in Lung Using PET (Positron Emission Tomography) In Healthy
Taurine
go.drugbank.com/drugs/DB01956ApprovedInvestigationalNutraceutical[A31396] This conditional amino acid can be either be manufactured by the body or obtained in the diet mainly by the consumption of fish and meat. … Taurine, whose chemical name is 2-aminoethanesulfonic acid, is one of the most abundant amino acids in several organs. It plays important role in essential biological processes.
Mixtures: SmofKabiven N-Plus zentral Emulsion zur Infusion, SmofKabiven N-Plus zentral elektrolytfrei Emulsion zur InfusionSTI-1499
go.drugbank.com/drugs/DB16487InvestigationalSTI-1499 (COVI-GUARD was under investigation in clinical trial NCT04454398 to evaluate its safety and efficacy in patients with moderate COVID-19.
Imipenem
go.drugbank.com/drugs/DB01598ApprovedInvestigationalImipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. … Similar compounds include [meropenem], known for having greater activity against Gram negative bacteria, and the newer [ertapenem] which exhibits a longer half-life due to increased binding to plasma proteins
Synonyms: N-formimidoylthienamycin, N-formimidoyl thienamycinMethysergide
go.drugbank.com/drugs/DB00247ApprovedWithdrawnIt antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. … An ergot derivative that is a congener of lysergic acid diethylamide.
Synonyms: (+)-N-(1-(Hydroxymethyl)propyl)-1-methyl-D-lysergamide, 1-Methyl-D-lysergic acid butanolamideCategories: Heterocyclic Compounds with 4 or More RingsUdenafil
go.drugbank.com/drugs/DB06267ApprovedIt has been approved in South Korea and will be marketed under the brand name Zydena. It is not yet approved for use in the U.S., E.U., or Canada.
Categories: combinations of sulfonamides, Drugs Used in Erectile Dysfunction1,2-dichlorobenzene
go.drugbank.com/drugs/DB13963ApprovedWithdrawnThis derivative of benzene differs from the parent compound by the presence of two adjacent chlorine atoms. 1,2-dichlorobenzene is used as a precursor for agrochemicals, as a solvent for fullerenes, as … 1,2-Dichlorobenzene, also named ortho-dichlorobenzene, is an organic compound. It is a non-polar colorless liquid that is miscible in most organic solvents.
Synonyms: o-Dichlorbenzol, o-dichlorbenzeneCategories: Compounds used in a research, industrial, or household settingOxtriphylline
go.drugbank.com/drugs/DB01303ApprovedOxtriphylline is the choline salt form of [theophylline]. … It is marketed under the name Choledyl SA, and several forms of oxytriphylline have been discontinued. In the US, oxtriphylline is no longer available.
Categories: combinations of xanthinesSynonyms: Teofilinato de colina, Theophyllinate de cholineMethylphenobarbital
go.drugbank.com/drugs/DB00849ApprovedIt has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
Categories: combinations of barbituratesSynonyms: N-Methylphenobarbital