Search

Displaying results 2461 - 2470 of 10000 in total
  1. Drug

    Thrombin

    go.drugbank.com/drugs/DB11300
    ApprovedInvestigational

    Medical thrombin is a protein substance produced through a conversion reaction in which prothrombin of bovine origin is activated by tissue thromboplastin in the presence of calcium chloride. … Also known as coagulation factor II, thrombin is a serine protease that plays a physiological role in regulating hemostasis and maintaining blood coagulation.

    Synonyms: coagulation factor IIMixtures: SAN. VE TİC. LTD., TACHOSİL 5,5 MG/CM2 İNSAN FİBRİNOJENİ VE 2.0 IU/CM2 İNSAN TROMBİNİ İLAÇLI SÜNGER
  2. Indication

    Subcutaneous bacterial infection

    go.drugbank.com/conditions/DBCOND0106114
    Drugs: Ampicillin
    Synonyms: Bacterial infection of skin and subcutis
  3. Indication

    Atrial Fibrillation or Flutter

    go.drugbank.com/conditions/DBCOND0077970
    Drugs: Digitoxin · Hydroquinidine · Quinidine
    Synonyms: Atrial Fibrillation and Flutter, Atrial fibrillation and flutter (disorder)
  4. Indication

    Primary generalized tonic-clonic Seizures

    go.drugbank.com/conditions/DBCOND0021691
    Drugs: Lacosamide · Lamotrigine · Levetiracetam
    Synonyms: Primary generalized tonic-clonic Seizures, Primary generalized tonic-clonic Seizure
  5. Indication

    Generalized tonic-clonic status epilepticus

    go.drugbank.com/conditions/DBCOND0134168
    Drugs: Fosphenytoin
    Synonyms: Generalized tonic-clonic status epilepticus, Generalized tonic-clonic status epilepticus (finding)
  6. Drug

    Desogestrel

    go.drugbank.com/drugs/DB00304
    ApprovedInvestigational

    [A176342] The first approved drug containing desogestrel was developed by Organon USA Inc in 1972 and FDA approved in 1992.[L5762] … Desogestrel, a prodrug, is a third generation progestogen[A176315] and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada.

    Synonyms: 13-Ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-olMixtures: Desogestrel and Ethinyl Estradiol and Ethinyl Estradiol, Desogestrel and Ethinyl Estradiol and Ethinyl Estradiol
  7. Drug

    Balsam of Peru

    go.drugbank.com/drugs/DB11482
    ApprovedNutraceuticalVet approved

    [L2879] By Health Canada, the balsam of Peru is approved by the use of over-the-counter combination products and it is currently approved in veterinary products. … [L1113] By the EMA, the balsam of Peru is approved and categorized under the herbal medicine products.[F121]

    Mixtures: PainAway with natural peppermint and Balsam Peru, Stroke II SynergyCategories: Compounds used in a research, industrial, or household setting
  8. Indication

    Mercury Poisoning

    go.drugbank.com/conditions/DBCOND0029336
    Drugs: Succimer
    Synonyms: Toxic effects of mercury and its compounds, Toxic effect of mercury and its compounds
  9. Pathway

    Noncanonical Wnt/Ca2+ signaling

    smpdb.ca/view/SMP0468891
    Signaling

    DAG and calcium activate protein kinase C (PKC), which in turn activates cell-division cycle 43 (Cdc42). … Increased concentrations of calcium in the cytosol also stimulate calcineurin and CAMKII. Calcineurin activates NFAT, which leads to gene transcription.

    Drugs: Calcium · Magnesium cation
    Enzymes: TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
  10. Target

    Inactive phospholipase C-like protein 1

    go.drugbank.com/bio_entities/BE0001081
    TargetHumans

    Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. … Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity).

    Synonyms: Phospholipase C-deleted in lung carcinoma, Phospholipase C-related but catalytically inactive protein