Search
Emapalumab
go.drugbank.com/drugs/DB14724ApprovedInvestigationalEmapalumab, also known as NI-0501, is a fully human monoclonal antibody that targets interferon gamma. Emapalumab development was sponsored by NovImmune SA, further developed by Sobi and FDA approved on November 20, 2018. The approval of...
Attapulgite
go.drugbank.com/drugs/DB01574ApprovedVet approvedWithdrawnFor that reason, it has often been used in antidiarrheal medications. Until 2003, it was the active ingredient used in Kaopectate, before that product was reformulated with bismuth subsalicylate.
Mixtures: Donnagel-PG CapRibavirin
go.drugbank.com/drugs/DB00811ApprovedInvestigationalas an adjunct therapy to various first-line and second-line combination therapies recommended for each genotypes. … Additionally, including ribavirin in the regimen can increase the risk of anemia.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UsePromethazine
go.drugbank.com/drugs/DB01069ApprovedInvestigational[A189901] Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting. … Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of [phenothiazine] that was developed in France in 1946.
Categories: Antihistamines for Topical Use, Antihistamines for Systemic UseGrazoprevir
go.drugbank.com/drugs/DB11575ApprovedGrazoprevir is an inhibitor of NS3/4A, a serine protease enzyme, encoded by HCV genotypes 1 and 4 [synthesis]. … It can be used in patients with compensated cirrhosis, human immunodeficiency virus co-infection, or severe kidney disease.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseTMC-310911
go.drugbank.com/drugs/DB15623InvestigationalTMC-310911 has shown marked activity against a variety of HIV-1 strains, including multi-PI-resistant strains, and may be less likely to generate resistance, making it a potentially desirable therapy for … both treatment-naive and PI-experienced patients.
Categories: Antivirals for Systemic Use, Experimental Unapproved Treatments for COVID-19Altretamine
go.drugbank.com/drugs/DB00488ApprovedWithdrawnAn alkylating agent proposed as an antineoplastic. It also acts as a chemosterilant for male houseflies and other insects.
Ivabradine
go.drugbank.com/drugs/DB09083ApprovedInvestigationalIvabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus rhythm with resting heart rate … Therefore, as ivabradine is designed as a "pure" heart rate-lowering drug by selectively acting on the If channels, it may offer a more favorable side effect profile due to its lower likelihood of causing
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBoron
go.drugbank.com/drugs/DB11203ApprovedInvestigationalIt is also found for applications including ceramics, high-hardness or abrasive compounds, metal coatings, detergents, bleaching agents, insecticides, semiconductors, magnets, wood preservatives, and an … additive in glass fibers of boron-containing fiberglass for insulation and structural materials.
Mixtures: BIOGROW MINMirtazapine
go.drugbank.com/drugs/DB00370ApprovedInvestigational[T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy. … It may improve the symptoms of neurological disorders, reverse weight loss caused by medical conditions, improve sleep, and prevent nausea and vomiting after surgery.[A177811]
Categories: Antidepressive Agents Indicated for Depression, Cytochrome P-450 Substrates