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Norgestrel
go.drugbank.com/drugs/DB09389ApprovedNorgestrel is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception. Norgestrel is composed of a racemic mixture of two stereoisomers, dextronorgestrel and levonorgestrel. However, only t...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMagnesium acetate tetrahydrate
go.drugbank.com/drugs/DB09409ApprovedWithdrawnMagnesium acetate tetrahydrate is a hydrated form of anhydrous magnesium acetate salt with the chemical formula of Mg(CH3COO)2 • 4H2O. As a salt form of magnesium, magnesium acetate is one of the bioavailable forms of magnesium and forms...
Phenyl salicylate
go.drugbank.com/drugs/DB11071ApprovedPhenyl salicylate is a 2-hydroxybenzoic acid phenyl ester. It is utilized in some manufacturing processes of polymers, lacquers, adhesives, waxes, as well as polishes. It is an active ingredient in some pharmaceutical products as a mild ...
Mixtures: UR N-C Urinary AntisepticSelenious acid
go.drugbank.com/drugs/DB11127ApprovedSelenious acid is the acid form of sodium selenite, a form of selenium . Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general hea...
Mixtures: Addamel N, ADDAMEL NButamben
go.drugbank.com/drugs/DB11148ApprovedWithdrawnButamben is a local anesthetic in the form of n-butyl-p-aminobenzoate.
Dihydroergocornine
go.drugbank.com/drugs/DB11273ApprovedDihydroergocornine is one of the dihydrogenated ergot compounds that present very large hypotensive effects. It is an artificial derivative of the crude extract of ergot and later purified, ergocornine. The formation of dihydroergocornin...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesOleandomycin
go.drugbank.com/drugs/DB11442ExperimentalVet approvedOleandomycin is a macrolide antibiotic, though it is less effective than erythromycin. It is synthesized from strains of Streptomyces antibioticus.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsSarafloxacin
go.drugbank.com/drugs/DB11491ApprovedVet approvedWithdrawnSarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsDifloxacin
go.drugbank.com/drugs/DB11511ExperimentalVet approvedDifloxacin is a synthetic fluoroquinolone used in veterinary. As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration. However, it presents a reduced efficacy when compared to oth...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesElbasvir
go.drugbank.com/drugs/DB11574ApprovedElbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). HCV is a single-stranded RNA virus that is c...
Categories: P-glycoprotein inhibitors, P-glycoprotein substrates